TY  - JOUR
AU  - Cirulli, Elizabeth T
AU  - Nicoletti, Paola
AU  - Abramson, Karen
AU  - Andrade, Raul J
AU  - Bjornsson, Einar S
AU  - Chalasani, Naga
AU  - Fontana, Robert J
AU  - Hallberg, Pär
AU  - Li, Yi Ju
AU  - Lucena, M Isabel
AU  - Long, Nanye
AU  - Molokhia, Mariam
AU  - Nelson, Matthew R
AU  - Odin, Joseph A
AU  - Pirmohamed, Munir
AU  - Rafnar, Thorunn
AU  - Serrano, Jose
AU  - Stefánsson, Kári
AU  - Stolz, Andrew
AU  - Daly, Ann K
AU  - Aithal, Guruprasad P
AU  - Watkins, Paul B
PY  - 2019
DO  - 10.1053/j.gastro.2019.01.034
UR  - http://hdl.handle.net/10668/13437
T2  - Gastroenterology
AB  - We performed genetic analyses of a multiethnic cohort of patients with idiosyncratic drug-induced liver injury (DILI) to identify variants associated with susceptibility. We performed a genome-wide association study of 2048 individuals with DILI...
LA  - en
PB  - Elsevier
KW  - Amino Acid Change
KW  - GWAS
KW  - Inflammation
KW  - Mutation
KW  - Adult
KW  - Black or african american
KW  - Amoxicillin
KW  - Anti-bacterial agents
KW  - Case-control studies
KW  - Chemical and drug induced liver injury
KW  - Clavulanic acid
KW  - Female
KW  - Gene frequency
KW  - Genome-wide association study
KW  - HLA-A2 antigen
KW  - HLA-DRB1 chains
KW  - Hispanic or latino
KW  - Humans
KW  - Male
KW  - Middle aged
KW  - Mutation, missense
KW  - Polymorphism, single nucleotide
KW  - Protein tyrosine phosphatase, non-Receptor type 22
KW  - Risk factors
KW  - White people
TI  - A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury.
TY  - research article
VL  - 156
ER  -