RT Journal Article T1 Hepatitis E Infection in HIV-Infected Patients. A1 Rivero-Juarez, Antonio A1 Lopez-Lopez, Pedro A1 Frias, Mario A1 Rivero, Antonio K1 HEV K1 HIV K1 Diagnosis K1 Epidemiology K1 Prevention K1 Treatment K1 Zoonoses AB The hepatitis E virus (HEV) represents a major cause of acute hepatitis worldwide. The majority of HEV cases occur in low-income countries, mainly Asia and Africa, where HEV causes large outbreaks associated with the consumption of contaminated water and high mortality in specific populations. In high-income countries, HEV infection is considered a zoonotic disease that is linked to the consumption of contaminated food. Although a high proportion of cases have self-limiting asymptomatic or subclinical infections, immunosuppression may modify the pathogenesis and clinical impact of this emerging disease. Here, we review the current knowledge about the epidemiology, diagnosis, clinical manifestations, management and prevention of HEV infection in HIV-infected subjects. Despite the increasing knowledge about the pathogenesis, epidemiology and clinical impact of HEV infection, several major factors are faced by HIV-infected patients, including treatment recommendations, immunization and risk practices. PB Frontiers Research Foundation SN 1664-302X YR 2019 FD 2019-06-05 LK http://hdl.handle.net/10668/14237 UL http://hdl.handle.net/10668/14237 LA en NO Rivero-Juarez A, Lopez-Lopez P, Frias M, Rivero A. Hepatitis E Infection in HIV-Infected Patients. Front Microbiol. 2019 Jun 26;10:1425 DS RISalud RD Mar 12, 2025