RT Journal Article
T1 Procalcitonin (PCT) levels for ruling-out bacterial coinfection in ICU patients with influenza: A CHAID decision-tree analysis.
A1 Rodríguez, Alejandro H
A1 Avilés-Jurado, Francesc X
A1 Díaz, Emili
A1 Schuetz, Philipp
A1 Trefler, Sandra I
A1 Solé-Violán, Jordi
A1 Cordero, Lourdes
A1 Vidaur, Loreto
A1 Estella, Ángel
A1 Pozo Laderas, Juan C
A1 Socias, Lorenzo
A1 Vergara, Juan C
A1 Zaragoza, Rafael
A1 Bonastre, Juan
A1 Guerrero, José E
A1 Suberviola, Borja
A1 Cilloniz, Catia
A1 Restrepo, Marcos I
A1 Martín-Loeches, Ignacio
A1 SEMICYUC/GETGAG Working Group, 
K1 CHAID analysis
K1 Community-acquired pneumonia
K1 Influenza A(H1N1)pmd
K1 Procalcitonin
K1 Prognosis
K1 Respiratory coinfection
K1 Septic shock
AB To define which variables upon ICU admission could be related to the presence of coinfection using CHAID (Chi-squared Automatic Interaction Detection) analysis. A secondary analysis from a prospective, multicentre, observational study (2009-2014) in ICU patients with confirmed A(H1N1)pdm09 infection. We assessed the potential of biomarkers and clinical variables upon admission to the ICU for coinfection diagnosis using CHAID analysis. Performance of cut-off points obtained was determined on the basis of the binominal distributions of the true (+) and true (-) results. Of the 972 patients included, 196 (20.3%) had coinfection. Procalcitonin (PCT; ng/mL 2.4 vs. 0.5, p  PCT has a high negative predictive value (94%) and lower PCT levels seems to be a good tool for excluding coinfection, particularly for patients without shock.
YR 2015
FD 2015-12-15
LK http://hdl.handle.net/10668/9678
UL http://hdl.handle.net/10668/9678
LA en
DS RISalud
RD Mar 14, 2025