RT Journal Article
T1 Multifocal ERG Guiding Therapy in a Case of Hydroxychloroquine Premaculopathy.
A1 Sáez-Moreno, José Antonio
A1 Domínguez-Hidalgo, Concepción
A1 Rodríguez-Ferrer, José Manuel
K1 Visión de colores
K1 Electrorretinografía
K1 Femenino
K1 Fondo de ojo
K1 Humanos
K1 Hidroxicloroquina
K1 Lupus eritematoso sistémico
K1 Remisión y consulta
K1 Agudeza visual
K1 Pruebas del campo visual
AB We report the case of a 28-year-old female treated for systemic lupus erythematosus with hydroxychloroquine (200 mg/day) for 11 years. She was visually asymptomatic, with normal fundus appearance, normal colour vision testing findings, 20/20 visual acuity in both eyes, and only mild central bilateral defects on 10-2 perimetry. Multifocal electroretinography (mfERG) showed low density values for ring 1 in both eyes. Because the patient had not previously responded to alternative treatments and in consultation with her physician, the hydroxychloroquine dose was reduced to 200 mg four days/week. Four serial mfERGs performed at 4, 18, 25, and 34 months after dose reduction showed a progressive improvement in the definition and density of the responses until they were normalized at the third mfERG (25 months after hydroxychloroquine dose reduction). The fourth and final mfERG at 34 months confirmed the recovery in both eyes. Perimetry defects were mostly normalized. These results demonstrate the importance of mfERG for the safe management of patients under long-term hydroxychloroquine treatment.
PB Hindawi Publishing Corporation
YR 2015
FD 2015-09-21
LK http://hdl.handle.net/10668/2557
UL http://hdl.handle.net/10668/2557
LA en
NO Sáez-Moreno JA, Domínguez-Hidalgo C, Rodríguez-Ferrer JM. Multifocal ERG Guiding Therapy in a Case of Hydroxychloroquine Premaculopathy. Case Rep Ophthalmol Med; 2015:656928
NO Journal Article;
DS RISalud
RD Apr 6, 2025