TY  - JOUR
AU  - Castejón-Vega, Beatriz
AU  - Battino, Maurizio
AU  - Quiles, José L.
AU  - Bullon, Beatriz
AU  - Cordero, Mario D.
AU  - Bullón, Pedro
PY  - 2021
DO  - 10.3390/antiox10010095
UR  - http://hdl.handle.net/10668/4019
T2  - Antioxidants
AB  - The Papillon-Lefèvre syndrome (PLS) is a rare autosomal recessive disorder caused by mutations in the Cathepsin C (CTSC) gene, characterized by periodontitis and palmoplantar hyperkeratosis. The main inflammatory deficiencies include oxidative stress...
LA  - en
PB  - MDPI
KW  - Papillon–Lefèvre syndrome
KW  - Mitochondria
KW  - Coenzyme Q10
KW  - Enfermedad de Papillon-Lefevre
KW  - Mitocondrias
KW  - Ubiquinona
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Peptide Hydrolases::Cathepsins::Cathepsin C
KW  - Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Oxygen Compounds::Reactive Oxygen Species
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Mutation
KW  - Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Fibroblasts
KW  - Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolism::Oxidative Stress
KW  - Medical Subject Headings::Diseases::Stomatognathic Diseases::Mouth Diseases::Periodontal Diseases::Periodontitis
KW  - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Mitochondria
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Drug Administration Routes::Administration, Topical
KW  - Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Oxygen Consumption
KW  - Medical Subject Headings::Technology and Food and Beverages::Food and Beverages::Food::Dietary Supplements
KW  - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::DNA::DNA, Circular::DNA, Mitochondrial
TI  - Potential Role of the Mitochondria for the Dermatological Treatment of Papillon-Lefèvre
TY  - research article
ER  -