TY - JOUR AU - Navas, Arturo AU - Jannus, Fatin AU - Fernández, Belén AU - Cepeda, Javier AU - Medina O'Donnell, Marta AU - Díaz-Ruiz, Luis AU - Sánchez-González, Cristina AU - Llopis, Juan AU - Seco, José M AU - Rufino-Palomares, E AU - Lupiáñez, José Antonio AU - Gómez-Ruiz, Santiago AU - Quiles, José Luis AU - Battino, Maurizio AU - Choquesillo-Lazarte, Duane AU - Ruiz-Muelle, Ana Belén AU - Fernández, Ignacio AU - Reyes-Zurita, Fernando AU - Rodríguez-Diéguez, Antonio PY - 2020 DO - 10.3390/ijms21093146 UR - http://hdl.handle.net/10668/15497 T2 - International journal of molecular sciences AB - We have designed and synthesized two novel cobalt coordination compounds using bumetanide (bum) and indomethacin (ind) therapeutic agents. The anti-inflammatory effects of cobalt metal complexes with ind and bum were assayed in lipopolysaccharide... LA - en KW - bumetadine KW - cobalt KW - coordination compound KW - diabetes KW - indomethacin KW - inflammatory KW - single-ion magnet KW - Algorithms KW - Animals KW - Anti-Inflammatory Agents KW - Cell Cycle Checkpoints KW - Cell Survival KW - Dose-Response Relationship, Drug KW - Drug Design KW - Hypoglycemic Agents KW - Magnets KW - Mice KW - Models, Chemical KW - Models, Molecular KW - Molecular Conformation KW - Nitric Oxide KW - RAW 264.7 Cells KW - Solubility KW - Structure-Activity Relationship TI - Designing Single-Molecule Magnets as Drugs with Dual Anti-Inflammatory and Anti-Diabetic Effects. TY - research article VL - 21 ER -