TY - JOUR AU - Amadoz, Alicia AU - Hidalgo, Marta R AU - Çubuk, Cankut AU - Carbonell-Caballero, José AU - Dopazo, Joaquín PY - 2019 DO - 10.1093/bib/bby040 UR - http://hdl.handle.net/10668/12548 T2 - Briefings in bioinformatics AB - Understanding the aspects of cell functionality that account for disease mechanisms or drug modes of action is a main challenge for precision medicine. Classical gene-based approaches ignore the modular nature of most human traits, whereas... LA - en KW - disease mechanism KW - mathematical models KW - networks KW - signaling pathways KW - systems biology KW - transcriptomics KW - Algorithms KW - Humans KW - Postmortem Changes KW - Signal Transduction KW - Systems Biology KW - Transcriptome TI - A comparison of mechanistic signaling pathway activity analysis methods. TY - research article VL - 20 ER -