TY - JOUR AU - Pastor-Villaescusa, Belen AU - Canete, M. Dolores AU - Caballero-Villarraso, Javier AU - Hoyos, Rayal AU - Latorre, Miriam AU - Vazquez-Cobela, Rocio AU - Plaza-Diaz, Julio AU - Maldonado, Jose AU - Bueno, Gloria AU - Leis, Rosaura AU - Gil, Angel AU - Canete, Ramon AU - Aguilera, Concepcion M. PY - 2017 DO - 10.1542/peds.2017-1205 SN - 0031-4005 UR - https://hdl.handle.net/10668/25879 T2 - Pediatrics AB - OBJECTIVES: Metformin has shown its effectiveness in treating obesity in adults. However, little research has been conducted in children, with a lack of attention on pubertal status. The objectives were to determine whether oral metformin treatment... LA - en PB - Amer acad pediatrics KW - Insulin-resistant adolescents KW - Metabolic syndrome KW - Endothelial function KW - Glucose-tolerance KW - Oxidative stress KW - Term treatment KW - Hyperinsulinemia KW - Overweight KW - Markers KW - Weight TI - Metformin for Obesity in Prepubertal and Pubertal Children: A Randomized Controlled Trial TY - research article VL - 140 ER -