RT Journal Article
T1 Clinical Characteristics of Patients with Spondyloarthritis in Japan in Comparison with Other Regions of the World.
A1 Kishimoto, Mitsumasa
A1 Yoshida, Kazuki
A1 Ichikawa, Naomi
A1 Inoue, Hisashi
A1 Kaneko, Yuko
A1 Kawasaki, Taku
A1 Matsui, Kazuo
A1 Morita, Mitsuhiro
A1 Suda, Masei
A1 Tada, Kurisu
A1 Takizawa, Naoho
A1 Tamura, Naoto
A1 Taniguchi, Atsuo
A1 Taniguchi, Yoshinori
A1 Tsuji, Shigeyoshi
A1 Haji, Yoichiro
A1 Rokutanda, Ryo
A1 Yanaoka, Haruyuki
A1 Cheung, Peter P
A1 Gu, Jieruo
A1 Kim, Tae-Hwan
A1 Luo, Shue-Fen
A1 Okada, Masato
A1 Lopez Medina, Clementina
A1 Molto, Anna
A1 Dougados, Maxime
A1 Kobayashi, Shigeto
A1 van der Heijde, Desiree
A1 Tomita, Tetsuya
K1 Ankylosing spondylitis
K1 Axial spondyloarthritis
K1 Classification criteria
K1 Peripheral spondyloarthritis
K1 Psoriatic arthritis
AB To delineate clinical characteristics of patients with spondyloarthritis (SpA) in Japan in comparison to other areas of the world. Using the ASAS-COMOSPA (Assessment of Spondyloarthritis international Society-COMOrbidities in SPondyloArthritis) data, an international cross-sectional observational study of patients with SpA, we analyzed information on demographics, disease characteristics, comorbidities, and risk factors. Patients were classified by region: Japan, other Asian countries (China, Singapore, South Korea, Taiwan), and non-Asian countries (Europe, the Americas, Africa). Patient characteristics, including diagnosis and treatment, were compared. Among 3984 patients included in the study, 161 were from centers in Japan, 933 from other Asian countries, and 2890 from other regions. Of patients with SpA in Japan, 42 (26.1%) had peripheral SpA, substantially more than in other countries. This trend was explained by the predominance of psoriatic arthritis (PsA) among Japanese patients with SpA. In contrast to the relatively low number in Japan, 54% of patients from other Asian countries had pure axial SpA (axSpA) without peripheral features. HLA-B27 testing, considered an integral part of the classification of axSpA, was performed in only 63.6% of Japanese patients with axSpA. More than half of Japanese patients with axSpA were classified using imaging criteria. In our study, there was a more substantial number of peripheral SpA cases observed in Japan compared to other parts of Asia and other regions of the world. Aside from ethnic differences, increasing recognition of PsA in Japan, as well as a potential underdiagnosis of axSpA due to the insufficient use of HLA-B27 testing, may partly explain regional discrepancies.
PB Journal of Rheumatology Publishing Co. Ltd.
SN 0315-162X
YR 2018
FD 2018-10-11
LK http://hdl.handle.net/10668/13571
UL http://hdl.handle.net/10668/13571
LA en
NO Kishimoto M, Yoshida K, Ichikawa N, Inoue H, Kaneko Y, Kawasaki T, et al.  Clinical Characteristics of Patients with Spondyloarthritis in Japan in Comparison with Other Regions of the World. J Rheumatol. 2019 Aug;46(8):896-903
DS RISalud
RD Apr 12, 2025