TY - JOUR AU - Jiménez-Jáimez, Juan AU - Macías-Ruiz, Rosa AU - Bermúdez-Jiménez, Francisco AU - Rubini-Costa, Ricardo AU - Ramírez-Taboada, Jessica AU - García Flores, Paula Isabel AU - Gallo-Padilla, Laura AU - Mediavilla García, Juan Diego AU - Morales García, Concepción AU - Moreno Suárez, Sara AU - Fignani Molina, Celia AU - Álvarez López, Miguel AU - Tercedor, Luis PY - 2020 DO - 10.1038/s41598-020-78360-9 UR - http://hdl.handle.net/10668/3445 T2 - Scientific Reports AB - SARS-CoV-2 is a rapidly evolving pandemic causing great morbimortality. Medical therapy with hydroxicloroquine, azitromycin and protease inhibitors is being empirically used, with reported data of QTc interval prolongation. Our aim is to assess QT... LA - en PB - Springer Nature KW - COVID-19 KW - Anti-bacterial agents KW - Antimalarials KW - Azithromycin KW - Drug therapy, combination KW - Antiviral agents KW - Farmacorresistencia bacteriana KW - Antimaláricos KW - Azitromicina KW - Quimioterapia combinada KW - Antivirales KW - Factores de riesgo KW - Medical Subject Headings::Persons::Persons::Age Groups::Adult KW - Medical Subject Headings::Persons::Persons::Age Groups::Adult::Aged KW - Medical Subject Headings::Persons::Persons::Age Groups::Adult::Aged::Aged, 80 and over KW - Anti-Bacterial Agents KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Antiparasitic Agents::Antiprotozoal Agents::Antimalarials KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Antiviral Agents KW - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Lactones::Macrolides::Erythromycin::Azithromycin KW - Medical Subject Headings::Diseases::Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections KW - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Critical Illness KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Drug Therapy, Combination KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Techniques, Cardiovascular::Heart Function Tests::Electrocardiography KW - Medical Subject Headings::Check Tags::Female KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 2-Ring::Quinolines::Aminoquinolines::Chloroquine::Hydroxychloroquine KW - Medical Subject Headings::Diseases::Cardiovascular Diseases::Heart Diseases::Arrhythmias, Cardiac::Long QT Syndrome KW - Medical Subject Headings::Check Tags::Male KW - Medical Subject Headings::Persons::Persons::Age Groups::Adult::Middle Aged KW - Medical Subject Headings::Chemicals and Drugs::Polycyclic Compounds::Bridged Compounds::Bicyclo Compounds::Bicyclo Compounds, Heterocyclic::Azabicyclo Compounds::beta-Lactams::Penicillins::Penicillin G::Ampicillin::Amoxicillin::Amoxicillin-Potassium... KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Enzyme Inhibitors::Protease Inhibitors KW - Medical Subject Headings::Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Epidemiologic Factors::Causality::Risk Factors KW - Medical Subject Headings::Diseases::Cardiovascular Diseases::Heart Diseases::Arrhythmias, Cardiac::Ventricular Fibrillation KW - Medical Subject Headings::Persons::Persons::Age Groups::Adult::Young Adult TI - Absence of relevant QT interval prolongation in not critically ill COVID-19 patients TY - research article ER -