RT Journal Article
T1 A pleiotropic variant in DNAJB4 is associated with multiple myeloma risk.
A1 Dicanio, Marco
A1 Giaccherini, Matteo
A1 Clay-Gilmour, Alyssa
A1 Macauda, Angelica
A1 Sainz, Juan
A1 Machiela, Mitchell J
A1 Rybicka-Ramos, Malwina
A1 Norman, Aaron D
A1 Tyczyńska, Agata
A1 Chanock, Stephen J
A1 Barington, Torben
A1 Kumar, Shaji K
A1 Bhatti, Parveen
A1 Cozen, Wendy
A1 Brown, Elizabeth E
A1 Suska, Anna
A1 Haastrup, Eva K
A1 Orlowski, Robert Z
A1 Dudziński, Marek
A1 Garcia-Sanz, Ramon
A1 Kruszewski, Marcin
A1 Martinez-Lopez, Joaquin
A1 Beider, Katia
A1 Iskierka-Jazdzewska, Elżbieta
A1 Pelosini, Matteo
A1 Berndt, Sonja I
A1 Raźny, Małgorzata
A1 Jamroziak, Krzysztof
A1 Rajkumar, S Vincent
A1 Jurczyszyn, Artur
A1 Vangsted, Annette Juul
A1 Collado, Pilar Garrido
A1 Vogel, Ulla
A1 Hofmann, Jonathan N
A1 Petrini, Mario
A1 Butrym, Aleksandra
A1 Slager, Susan L
A1 Ziv, Elad
A1 Subocz, Edyta
A1 Giles, Graham G
A1 Andersen, Niels Frost
A1 Mazur, Grzegorz
A1 Watek, Marzena
A1 Lesueur, Fabienne
A1 Hildebrandt, Michelle A T
A1 Zawirska, Daria
A1 Ebbesen, Lene Hyldahl
A1 Marques, Herlander
A1 Gemignani, Federica
A1 Dumontet, Charles
A1 Várkonyi, Judit
A1 Buda, Gabriele
A1 Nagler, Arnon
A1 Druzd-Sitek, Agnieszka
A1 Wu, Xifeng
A1 Kadar, Katalin
A1 Camp, Nicola J
A1 Grzasko, Norbert
A1 Waller, Rosalie G
A1 Vachon, Celine
A1 Canzian, Federico
A1 Campa, Daniele
K1 genetic susceptibility
K1 multiple myeloma
K1 pleiotropy
K1 pleiotropy scan
K1 polymorphisms
AB Pleiotropy, which consists of a single gene or allelic variant affecting multiple unrelated traits, is common across cancers, with evidence for genome-wide significant loci shared across cancer and noncancer traits. This feature is particularly relevant in multiple myeloma (MM) because several susceptibility loci that have been identified to date are pleiotropic. Therefore, the aim of this study was to identify novel pleiotropic variants involved in MM risk using 28 684 independent single nucleotide polymorphisms (SNPs) from GWAS Catalog that reached a significant association (P 
YR 2022
FD 2022-10-01
LK http://hdl.handle.net/10668/22106
UL http://hdl.handle.net/10668/22106
LA en
DS RISalud
RD Apr 8, 2025