RT Journal Article T1 Humoral Response to Third Dose of SARS-CoV-2 Vaccines in the CKD Spectrum. A1 Quiroga, Borja A1 Soler, Maria Jose A1 Ortiz, Alberto A1 Orero, Esther A1 Tejedor, Sandra A1 Jarava-Mantecon, Carlos Jesus A1 Gomez-Perez, Virginia Olinda A1 Marin-Franco, Antonio Jose A1 Alfaro-Sanchez, Christian A1 Puerta-Carretero, Marta A1 Jaldo-Rodriguez, Maria Teresa A1 Carnerero-Di-Riso, Manuel Antonio A1 Martinez, Shaira A1 Caldeon-Gonzalez, Carmen A1 Cervienka, Michal A1 Macias-Carmona, Nicolas A1 Arroyo, David A1 Perez-Del-Valle, Katia M A1 de-Arriba, Gabriel A1 Mazuecos, Auxiliadora A1 Cazorla, Juan Manuel A1 Pereira, Monica A1 Gonzalez-Parra, Emilio A1 Sanchez-Marquez, Maria Gabriela A1 Lancho-Novillo, Carolina A1 Toyos-Ruiz, Carmen A1 Aguilar-Cervera, Maria Cinta A1 Muñoz-Ramos, Patricia A1 Sanchez-Horrillo, Ana A1 Jimeno-Martin, Isabel A1 Toapanta, Nestor A1 Cigarran-Guldris, Secundino A1 Folgueiras-Lopez, Montserrat A1 Valero-San-Cecilio, Rosalia A1 Villacorta-Linaza, Blanca A1 Minguela-Pesquera, Ignacio A1 Santana-Estupiñan, Raquel A1 Zamora, Rocio A1 Soriano, Sagrario A1 Muñoz-de-Bustillo, Eduardo A1 Pizarro-Sanchez, Maria Soledad A1 Martinez-Puerto, Ana Isabel A1 Yugueros, Alejandra A1 Muñiz-Pacios, Laura A1 Leyva, Alba A1 Rojas, Jose A1 Gansevoort, Ron T A1 de-Sequera, Patricia K1 COVID-19 K1 SARS-CoV-2 K1 Anti-Spike K1 Chronic kidney disease K1 Hemodialysis K1 Kidney transplantation K1 Peritoneal dialysis K1 Vaccination AB Information on the effect of a third dose of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine in advanced CKD is incomplete (1). We assessed the humoral response up to 6 months after receipt of two or three doses of the SARS-CoV-2 vaccine across the CKD spectrum. SENOVAC is a prospective, multicentric study of cohorts of patients with CKD: kidney transplant, hemodialysis (HD), peritoneal dialysis (PD), and nondialysis CKD (eGFR <30 ml/min per 1.73 m2) (2,3). Patients were vaccinated against SARS-CoV-2 during routine clinical care. Some patients received a third dose of an mRNA vaccine. This depended on the timing of vaccination drives by local health authorities. We assessed anti-Spike antibodies (CLIA, Covid-19 Spike Quantitative Virla IgG Monotest; Vircell SL, Spain) kinetics at a prespecified 6-month time point after completing the original vaccination schedule (2,3). The study was approved by the ethics committee of Instituto de Investigación Sanitaria-Fundación Jiménez Díaz (ISFJD) (February 2021). PB American Society of Nephrology YR 2022 FD 2022-05-12 LK http://hdl.handle.net/10668/20489 UL http://hdl.handle.net/10668/20489 LA en NO Quiroga B, Soler MJ, Ortiz A, Orero E, Tejedor S, Mantecón CJJ, et al. Humoral Response to Third Dose of SARS-CoV-2 Vaccines in the CKD Spectrum. Clin J Am Soc Nephrol. 2022 Jun;17(6):872-876 DS RISalud RD Aug 18, 2025