RT Journal Article
T1 Radiobiology data of melanoma cells after low-energy neutron irradiation and boron compound administration.
A1 Pedrosa-Rivera, María
A1 Ruiz-Magaña, M José
A1 Álvarez, Patricia
A1 Porras, Ignacio
A1 Praena, Javier
A1 Sabariego, Manuel P
A1 Köster, Ulli
A1 Haertlein, Michael
A1 Forsyth, V Trevor
A1 Soldner, Torsten
A1 Ramírez, José C
A1 Jover, Clara
A1 Jimena, Daniel
A1 Osorio, Juan L
A1 Postuma, Ian
A1 Ruiz-Ruiz, Carmen
AB The cold neutron beam at the PF1b line at the Institut Laue-Langevin (ILL), without fast neutrons and a low contribution of gamma rays, is a very suitable facility to measure cell damage following low-energy neutron irradiation. The biological damage associated with the thermal and the boron doses can be obtained in order to evaluate the relative biological effectiveness (RBE) for Boron Neutron Capture Therapy. Three different experiments were carried out on the A375 melanoma cell line: the first one in a hospital LINAC, to obtain the reference radiation data, and the other two at the ILL, in which the damage to cells with and without boron compounds added was measured.
YR 2020
FD 2020-04-26
LK http://hdl.handle.net/10668/15540
UL http://hdl.handle.net/10668/15540
LA en
DS RISalud
RD Apr 11, 2025