TY - JOUR AU - López de la Oliva, Amada R. AU - Campos-Sandoval, José A. AU - Gómez-García, María C. AU - Cardona, Carolina AU - Martín-Rufián, Mercedes AU - Sialana, Fernando J. AU - Castilla, Laura AU - Bae, Narkhyun AU - Lobo, Carolina AU - Peñalver, Ana AU - García-Frutos, Marina AU - Carro, David AU - Enrique, Victoria AU - Paz, José C. AU - Mirmira, Raghavendra G. AU - Gutiérrez, Antonia AU - Alonso, Francisco J. AU - Segura, Juan A. AU - Matés, José M. AU - Lubec, Gert AU - Márquez, Javier PY - 2020 DO - 10.1038/s41598-020-58264-4 UR - http://hdl.handle.net/10668/3878 T2 - Scientific Reports AB - Glutaminase (GA) catalyzes the first step in mitochondrial glutaminolysis playing a key role in cancer metabolic reprogramming. Humans express two types of GA isoforms: GLS and GLS2. GLS isozymes have been consistently related to cell proliferation,... LA - en PB - Springer Nature KW - Translocation KW - Glutaminase KW - Cell Proliferation KW - Cell cycle KW - Mitochondria KW - Cancer KW - Translocación genética KW - Glutaminasa KW - Proliferación celular KW - Ciclo celular KW - Mitocondrias KW - Medical Subject Headings::Organisms::Eukaryota::Animals KW - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Transformed::COS Cells KW - Medical Subject Headings::Diseases::Neoplasms::Neoplastic Processes::Carcinogenesis KW - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Growth Processes::Cell Proliferation KW - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Amidohydrolases::Glutaminase KW - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Tumor Cells, Cultured::Cell Line, Tumor::Hep G2 Cells KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Diseases::Neoplasms KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Cycle::Cell Cycle Checkpoints KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Differentiation TI - Nuclear Translocation of Glutaminase GLS2 in Human Cancer Cells Associates with Proliferation Arrest and Differentiation TY - research article ER -