TY - JOUR AU - Fuzi, Miklos AU - Rodriguez Baño, Jesus AU - Toth, Akos PY - 2020 DO - 10.3389/fmicb.2020.00271 UR - http://hdl.handle.net/10668/3622 T2 - Frontiers in Microbiology AB - It is well-established that the spread of many multidrug-resistant (MDR) bacteria is predominantly clonal. Interestingly the international clones/sequence types (STs) of most pathogens emerged and disseminated during the last three decades. Strong... LA - en PB - Frontiers KW - Multidrug-resistant pathogens KW - Clonal dynamics KW - Fluoroquinolone resistance KW - Fitness cost KW - Virulence KW - Bacterias KW - Farmacorresistencia bacteriana múltiple KW - Clonal evolution KW - Fluoroquinolonas KW - Hospitales KW - DNA Topoisomerase IV KW - Mutación KW - Medical Subject Headings::Organisms::Bacteria::Endospore-Forming Bacteria::Gram-Positive Endospore-Forming Bacteria::Gram-Positive Endospore-Forming Rods::Staphylococcaceae::Staphylococcus::Staphylococcus aureus::Methicillin-Resistant Staphylococcus... KW - Medical Subject Headings::Organisms::Bacteria::Gram-Negative Bacteria::Gram-Negative Facultatively Anaerobic Rods::Enterobacteriaceae::Klebsiella::Klebsiella pneumoniae KW - Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 2-Ring::Quinolines::Quinolones::Fluoroquinolones KW - Medical Subject Headings::Phenomena and Processes::Microbiological Phenomena::Drug Resistance, Microbial KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Anti-Bacterial Agents KW - Medical Subject Headings::Organisms::Bacteria::Gram-Negative Bacteria::Gram-Negative Facultatively Anaerobic Rods::Enterobacteriaceae::Escherichia::Escherichia coli KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Mutation KW - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Toxins, Biological::Virulence Factors KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Clonal Evolution KW - Medical Subject Headings::Health Care::Health Care Facilities, Manpower, and Services::Health Facilities::Hospitals KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Toxic Actions::Noxae TI - Global Evolution of Pathogenic Bacteria With Extensive Use of Fluoroquinolone Agents TY - review article ER -