TY - JOUR AU - Salguero-Aranda, Carmen AU - Tapia-Limonchi, Rafael AU - Margot Cahuana, Gladys AU - Belen Hitos, Ana AU - Diaz, Irene AU - Hmadcha, Abdelkrim AU - Fraga, Mario AU - Martin, Franz AU - Soria, Bernat AU - Rigoberto Tejedo, Juan AU - Javier Bedoya, Francisco PY - 2016 DO - 10.3727/096368916X691178 SN - 0963-6897 UR - http://hdl.handle.net/10668/19335 T2 - Cell transplantation AB - Pancreatic and duodenal homeobox 1 (Pdx1) is a transcription factor that regulates the embryonic development of the pancreas and the differentiation toward beta cells. Previously, we have shown that exposure of mouse embryonic stem cells (mESCs) to... LA - en PB - Cognizant communication corp KW - Embryonic stem cells (ESCs) KW - Nitric oxide (NO) KW - Cell differentiation KW - Insulin-producing cells KW - Diabetes KW - Insulin-producing cells KW - In-vitro KW - Developmental regulators KW - Gene-expression KW - Es cells KW - Polycomb KW - Repression KW - Jarid2 KW - P300 KW - Prc2 TI - Differentiation of Mouse Embryonic Stem Cells Toward Functional Pancreatic beta-Cell Surrogates Through Epigenetic Regulation of Pdx1 by Nitric Oxide TY - research article VL - 25 ER -