TY - JOUR AU - Garrido, Maria Antonia AU - Perea, Francisco AU - Vilchez, Jose Ramon AU - Rodríguez, Teresa AU - Anderson, Per AU - Garrido, Federico AU - Ruiz-Cabello, Francisco AU - Aptsiauri, Natalia PY - 2021 DO - 10.3390/cancers13205046 SN - 2072-6694 UR - https://hdl.handle.net/10668/26347 T2 - Cancers AB - Total or partial loss of HLA class I antigens reduce the recognition of specific tumor peptides by cytotoxic T lymphocytes favoring cancer immune escape during natural tumor evolution. These alterations can be caused by genomic defects, such as loss... LA - en KW - HLA class I KW - antigen presentation KW - beta2-microglobulin KW - cancer immune escape KW - cancer immunotherapy KW - copy-neutral loss of heterozygosity (CN-LOH) KW - cytotoxic T-cells TI - Copy Neutral LOH Affecting the Entire Chromosome 6 Is a Frequent Mechanism of HLA Class I Alterations in Cancer. TY - research article VL - 13 ER -