TY  - JOUR
AU  - Torroglosa, Ana
AU  - Villalba-Benito, Leticia
AU  - Maria Fernandez, Raquel
AU  - Jose Moya-Jimenez, Maria
AU  - Antiñolo, Guillermo
AU  - Borrego, Salud
PY  - 2017
DO  - 10.18632/oncotarget.22473
UR  - http://hdl.handle.net/10668/19448
T2  - Oncotarget
AB  - Hirschsprung disease (HSCR, OMIM 142623) is a pathology that shows a lack of enteric ganglia along of the distal gastrointestinal tract. This aganglionosis is attributed to an abnormal proliferation, migration, differentiation and/or survival of...
LA  - en
PB  - Impact journals llc
KW  - Hirschsprung disease
KW  - DNMT3b
KW  - ENS development
KW  - P53
KW  - P21
KW  - Neural crest development
KW  - Embryonic stem-cells
KW  - Dna methyltransferases
KW  - Ret protooncogene
KW  - Cancer-cells
KW  - P53
KW  - Apoptosis
KW  - Differentiation
KW  - Methylation
KW  - Expression
TI  - Dnmt3b knock-down in enteric precursors reveals a possible mechanism by which this de novo methyltransferase is involved in the enteric nervous system development and the onset of Hirschsprung disease
TY  - research article
VL  - 8
ER  -