RT Journal Article
T1 Anaesthesia and cancer: can anaesthetic drugs modify gene expression?
A1 Raigon Ponferrada, Aida
A1 Guerrero Orriach, Jose Luis
A1 Malo Manso, Alfredo
A1 Sepúlveda Haro, Enrique
A1 Romero Molina, Salvador
A1 Fontaneda Heredia, Ana
A1 Baena Lopez, Manolo
A1 Cruz Mañas, Jose
K1 Anaesthesia
K1 Analgesia
K1 Cancer recurrence
K1 Metastases
K1 Anaesthetics
K1 Regional anaesthesia
K1 Opioid
K1 NSAIDs
K1 Anestesia en procedimientos quirúrgicos cardíacos
K1 Metástasis de la neoplasia
K1 Analgésicos opioides
K1 Antiinflamatorios no esteroideos
AB Cancer remains a primary cause of morbidity and mortality worldwide, and its incidence continues to increase. The most common cause of death in cancer patients is tumour recurrence. Surgery is the gold standard in the treatment of most tumours. However, cancer surgery can lead to the release of tumour cells into the systemic circulation. Surgical stress and several perioperative factors have been suggested to boost tumour growth, thereby increasing the risk of metastatic recurrence. Preclinical and clinical studies suggest that anaesthetics and adjuvants administered during the perioperative period may impact cancer recurrence and survival. This document summarises the current evidence regarding the effects of anaesthetic drugs and analgesic techniques on the immune system, systemic inflammatory response and tumour cells, as well as their impact on cancer recurrence.
PB Cancer Intelligence
YR 2020
FD 2020-07-27
LK http://hdl.handle.net/10668/3969
UL http://hdl.handle.net/10668/3969
LA en
NO Ponferrada AR, Orriach JLG, Manso AM, Haro ES, Molina SR, Heredia AF, et al. Anaesthesia and cancer: can anaesthetic drugs modify gene expression? Ecancermedicalscience. 2020 Jul 27;14:1080
DS RISalud
RD Apr 11, 2025