TY - JOUR AU - Roncero-Ramos, Irene AU - Gutierrez-Mariscal, Francisco M AU - Gomez-Delgado, Francisco AU - Villasanta-Gonzalez, Alejandro AU - Torres-Peña, Jose D AU - Cruz-Ares, Silvia De La AU - Rangel-Zuñiga, Oriol A AU - Luque, Raul M AU - Ordovas, Jose M AU - Delgado-Lista, Javier AU - Perez-Martinez, Pablo AU - Camargo, Antonio AU - Alcalá-Diaz, Juan F AU - Lopez-Miranda, Jose PY - 2021 DO - 10.1016/j.trsl.2021.07.001 UR - https://hdl.handle.net/10668/24452 T2 - Translational research : the journal of laboratory and clinical medicine AB - In order to assess whether previous hepatic IR (Hepatic-IRfasting) and beta-cell functionality could modulate type 2 diabetes remission and the need for starting glucose-lowering treatment, newly-diagnosed type 2 diabetes participants who had never... LA - en KW - ALT = alanine aminotransferase KW - AUC = area under curve KW - Adipo-IR = Adipose tissue insulin resistance index KW - BMI = body mass index KW - CHD = coronary heart disease KW - CORDIOPREV = CORonary Diet Intervention with Olive oil and cardiovascular PREVention KW - DBP = diastolic blood pressure KW - DI = disposition index KW - FFA = free fatty acids KW - HDL-c = high-density lipoprotein KW - Hepatic-IR(fasting) = hepatic insulin resistance index derived from fasting values KW - IGI = insulinogenic index KW - IR = insulin resistance KW - ISI = insulin sensitivity index KW - LDL-c = low-density lipoprotein KW - LF diet = low-fat diet KW - MISI = muscular insulin sensitivity index KW - MUFA = monounsaturated fatty acids KW - Med diet = Mediterranean diet KW - OGTT = oral glucose tolerance test KW - PUFA = polyunsaturated fatty acids KW - SBP = systolic blood pressure KW - T2DM = type 2 diabetes mellitus KW - TG = triglycerides KW - Alanine Transaminase KW - Diabetes Mellitus, Type 2 KW - Diet, Mediterranean KW - Fatty Acids KW - Female KW - Glucose Tolerance Test KW - Glycated Hemoglobin KW - Humans KW - Hypoglycemic Agents KW - Insulin Resistance KW - Insulin-Secreting Cells KW - Liver KW - Male KW - Middle Aged TI - Beta cell functionality and hepatic insulin resistance are major contributors to type 2 diabetes remission and starting pharmacological therapy: from CORDIOPREV randomized controlled trial. TY - research article VL - 238 ER -