TY  - JOUR
AU  - Renziehausen, Alexander
AU  - Wang, Hexiao
AU  - Rao, Bhavya
AU  - Weir, Lynda
AU  - Nigro, Cristiana Lo
AU  - Lattanzio, Laura
AU  - Merlano, Marco
AU  - Vega-Rioja, Antonio
AU  - Del Carmen Fernandez-Carranco, Maria
AU  - Hajji, Nabil
AU  - Matin, Rubeta
AU  - Harwood, Catherine
AU  - Li, Su
AU  - Sim, Van Ren
AU  - O'Neill, Kevin
AU  - Evans, Alan
AU  - Thompson, Alastair
AU  - Szlosarek, Peter
AU  - Fleming, Colin
AU  - Stebbing, Justin
AU  - Proby, Charlotte
AU  - Tzakos, Andreas G
AU  - Syed, Nelofer
AU  - Crook, Tim
PY  - 2018
DO  - 10.1038/s41388-018-0563-y
UR  - http://hdl.handle.net/10668/13242
T2  - Oncogene
AB  - Despite emergence of new systemic therapies, metastatic melanoma remains a challenging and often fatal form of skin cancer. The renin-angiotensin system (RAS) is a major physiological regulatory pathway controlling salt-water equilibrium,...
LA  - en
KW  - Amides
KW  - Angiotensin II
KW  - Angiotensin-Converting Enzyme Inhibitors
KW  - Animals
KW  - Antihypertensive Agents
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Cells, Cultured
KW  - DNA Methylation
KW  - Embryo, Nonmammalian
KW  - Fumarates
KW  - Humans
KW  - Imidazoles
KW  - Melanoma
KW  - Molecular Targeted Therapy
KW  - Neoplasm Metastasis
KW  - Pyridines
KW  - Receptor, Angiotensin, Type 1
KW  - Receptor, Angiotensin, Type 2
KW  - Renin-Angiotensin System
KW  - Xenograft Model Antitumor Assays
KW  - Zebrafish
TI  - The renin angiotensin system (RAS) mediates bifunctional growth regulation in melanoma and is a novel target for therapeutic intervention.
TY  - research article
VL  - 38
ER  -