TY - JOUR AU - Espinosa-Sánchez, Asunción AU - Suárez-Martínez, Elisa AU - Sánchez-Díaz, Laura AU - Carnero, Amancio PY - 2020 DO - 10.3389/fonc.2020.01533 UR - http://hdl.handle.net/10668/3591 T2 - Frontiers in Oncology AB - The theory of cancer stem cells (CSCs) proposes that the different cells within a tumor, as well as metastasis deriving from it, are originated from a single subpopulation of cells with self-renewal and differentiation capacities. These cancer stem... LA - en PB - Frontiers KW - CSC KW - Cancer KW - EMT KW - Stem cell-like pathways KW - Therapy KW - Células madre neoplásicas KW - Neoplasias KW - Transición epitelial-mesenquimal KW - Terapéutica KW - Medical Subject Headings::Anatomy::Cells::Stem Cells::Neoplastic Stem Cells KW - Medical Subject Headings::Diseases::Neoplasms KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Transdifferentiation::Epithelial-Mesenchymal Transition KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Phosphatidylinositol 3-Kinases KW - Medical Subject Headings::Psychiatry and Psychology::Behavior and Behavior Mechanisms::Motivation::Goals KW - Medical Subject Headings::Anatomy::Cells::Stem Cells::Neoplastic Stem Cells KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Signal Transduction KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Differentiation KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Transcription Factors KW - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Recurrence KW - Medical Subject Headings::Chemicals and Drugs::Pharmaceutical Preparations TI - Therapeutic Targeting of Signaling Pathways Related to Cancer Stemness TY - review article ER -