RT Journal Article
T1 Evaluation of Health-Related Quality of Life according to Carbohydrate Metabolism Status: A Spanish Population-Based Study (Di@bet.es Study)
A1 Marcuello, C.
A1 Calle-Pascual, A.L.
A1 Fuentes, M.
A1 Runkle, I.
A1 Soriguer, F.
A1 Goday, A.
A1 Bosch-Comas, A.
A1 Bordiú, E.
A1 Carmena, R.
A1 Casamitjana, R.
A1 Castaño, L.
A1 Castell, C.
A1 Catalá, M.
A1 Delgado, E.
A1 Franch, J.
A1 Gaztambide, S.
A1 Girbés, J.
A1 Gomis, R.
A1 Gutiérrez, G.
A1 López-Alba, A.
A1 Martínez-Larrad, M.T.
A1 Menéndez, E.
A1 Mora-Peces, I.
A1 Ortega, E.
A1 Pascual-Manich, G.
A1 Rojo-Martínez, G.
A1 Serrano-Rios, M.
A1 Valdés, S.
A1 Vázquez, J.A.
A1 Vendrell, J.
K1 España
K1 Calidad de Vida
K1 Estudios Transversales
K1 Muestreo
K1 Análisis de Regresión
K1 Modelos Logísticos
K1 Metabolismo de los Hidratos de Carbono
K1 Glucosa
AB Objective. To evaluate the association between diabetes mellitus and health-related quality of life (HRQOL) controlled for several sociodemographic and anthropometric variables, in a representative sample of the Spanish population. Methods. A population-based, cross-sectional, and cluster sampling study, with the entire Spanish population as the target population. Five thousand and forty-seven participants (2162/2885 men/women) answered the HRQOL short form 12 questionnaire (SF-12). The physical (PCS-12) and the mental component summary (MCS-12) scores were assessed. Subjects were divided into four groups according to carbohydrate metabolism status: normal, prediabetes, unknown diabetes (UNKDM), and known diabetes (KDM). Logistic regression analyses were conducted. Results. Mean PCS-12/MCS-12 values were 50.9 ± 8.5/47.6 ± 10.2, respectively. Men had higher scores than women in both PCS-12 (51.8 ± 7.2 versus 50.3 ± 9.2; P < 0.001) and MCS-12 (50.2 ± 8.5 versus 45.5 ± 10.8; P < 0.001). Increasing age and obesity were associated with a poorer PCS-12 score. In women lower PCS-12 and MCS-12 scores were associated with a higher level of glucose metabolism abnormality (prediabetes and diabetes), (P < 0.0001 for trend), but only the PCS-12 score was associated with altered glucose levels in men (P < 0.001 for trend). The Odds Ratio adjusted for age, body mass index (BMI) and educational level, for a PCS-12 score below the median was 1.62 (CI 95%: 1.2–2.19; P < 0.002) for men with KDM and 1.75 for women with KDM (CI 95%: 1.26–2.43; P < 0.001), respectively. Conclusion. Current study indicates that increasing levels of altered carbohydrate metabolism are accompanied by a trend towards decreasing quality of life, mainly in women, in a representative sample of Spanish population.
PB Hindawi Publishing Corporation
SN 1687-8337
YR 2012
FD 2012
LK http://hdl.handle.net/10668/1487
UL http://hdl.handle.net/10668/1487
LA es
NO Marcuello C, Calle-Pascual AL, Fuentes M, Runkle I, Soriguer F, Goday A, et al. Evaluation of Health-Related Quality of Life according to Carbohydrate Metabolism Status: A Spanish Population-Based Study (Di@bet.es Study). Int J Endocrinol.  2012: 2012; 872305. doi:10.1155/2012/872305
DS RISalud
RD Apr 19, 2025