%0 Journal Article
%A Marcuello, C.
%A Calle-Pascual, A.L.
%A Fuentes, M.
%A Runkle, I.
%A Soriguer, F.
%A Goday, A.
%A Bosch-Comas, A.
%A Bordiú, E.
%A Carmena, R.
%A Casamitjana, R.
%A Castaño, L.
%A Castell, C.
%A Catalá, M.
%A Delgado, E.
%A Franch, J.
%A Gaztambide, S.
%A Girbés, J.
%A Gomis, R.
%A Gutiérrez, G.
%A López-Alba, A.
%A Martínez-Larrad, M.T.
%A Menéndez, E.
%A Mora-Peces, I.
%A Ortega, E.
%A Pascual-Manich, G.
%A Rojo-Martínez, G.
%A Serrano-Rios, M.
%A Valdés, S.
%A Vázquez, J.A.
%A Vendrell, J.
%T Evaluation of Health-Related Quality of Life according to Carbohydrate Metabolism Status: A Spanish Population-Based Study (Di@bet.es Study)
%D 2012
%@ 1687-8337
%U http://hdl.handle.net/10668/1487
%X Objective. To evaluate the association between diabetes mellitus and health-related quality of life (HRQOL) controlled for several sociodemographic and anthropometric variables, in a representative sample of the Spanish population. Methods. A population-based, cross-sectional, and cluster sampling study, with the entire Spanish population as the target population. Five thousand and forty-seven participants (2162/2885 men/women) answered the HRQOL short form 12 questionnaire (SF-12). The physical (PCS-12) and the mental component summary (MCS-12) scores were assessed. Subjects were divided into four groups according to carbohydrate metabolism status: normal, prediabetes, unknown diabetes (UNKDM), and known diabetes (KDM). Logistic regression analyses were conducted. Results. Mean PCS-12/MCS-12 values were 50.9 ± 8.5/47.6 ± 10.2, respectively. Men had higher scores than women in both PCS-12 (51.8 ± 7.2 versus 50.3 ± 9.2; P < 0.001) and MCS-12 (50.2 ± 8.5 versus 45.5 ± 10.8; P < 0.001). Increasing age and obesity were associated with a poorer PCS-12 score. In women lower PCS-12 and MCS-12 scores were associated with a higher level of glucose metabolism abnormality (prediabetes and diabetes), (P < 0.0001 for trend), but only the PCS-12 score was associated with altered glucose levels in men (P < 0.001 for trend). The Odds Ratio adjusted for age, body mass index (BMI) and educational level, for a PCS-12 score below the median was 1.62 (CI 95%: 1.2–2.19; P < 0.002) for men with KDM and 1.75 for women with KDM (CI 95%: 1.26–2.43; P < 0.001), respectively. Conclusion. Current study indicates that increasing levels of altered carbohydrate metabolism are accompanied by a trend towards decreasing quality of life, mainly in women, in a representative sample of Spanish population.
%K España
%K Calidad de Vida
%K Estudios Transversales
%K Muestreo
%K Análisis de Regresión
%K Modelos Logísticos
%K Metabolismo de los Hidratos de Carbono
%K Glucosa
%~