TY  - JOUR
AU  - Kim, M
AU  - Jang, K
AU  - Miller, P
AU  - Picon-Ruiz, M
AU  - Yeasky, T M
AU  - El-Ashry, D
AU  - Slingerland, J M
PY  - 2017
DO  - 10.1038/onc.2017.4
UR  - https://hdl.handle.net/10668/24641
T2  - Oncogene
AB  - Cancer stem cells (CSC) appear to have increased metastatic potential, but mechanisms underlying this are poorly defined. Here we show that VEGFA induction of Sox2 promotes EMT and tumor metastasis. In breast lines and primary cancer culture, VEGFA...
LA  - en
KW  - Animals
KW  - Breast Neoplasms
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Female
KW  - Gene Expression Regulation, Neoplastic
KW  - Humans
KW  - Lung Neoplasms
KW  - Mice
KW  - Mice, Inbred BALB C
KW  - Mice, Nude
KW  - MicroRNAs
KW  - Neoplastic Stem Cells
KW  - SOXB1 Transcription Factors
KW  - Snail Family Transcription Factors
KW  - Vascular Endothelial Growth Factor A
TI  - VEGFA links self-renewal and metastasis by inducing Sox2 to repress miR-452, driving Slug.
TY  - research article
VL  - 36
ER  -