RT Journal Article
T1 Role of Multiparametric Prostate Magnetic Resonance Imaging before Confirmatory Biopsy in Assessing the Risk of Prostate Cancer Progression during Active Surveillance.
A1 Salguero, Joseba
A1 Gomez-Gomez, Enrique
A1 Valero-Rosa, Jose
A1 Carrasco-Valiente, Julia
A1 Mesa, Juan
A1 Martin, Cristina
A1 Campos-Hernandez, Juan Pablo
A1 Rubio, Juan Manuel
A1 Lopez, Daniel
A1 Requena, Maria Jose
K1 Active surveillance
K1 Active treatment
K1 Confirmatory biopsy reclassification
K1 Multiparametric prostate magnetic resonance imaging
K1 Progression risk
K1 Prostate cancer
AB To evaluate the impact of multiparametric magnetic resonance imaging (mpMRI) before confirmatory prostate biopsy in patients under active surveillance (AS). This retrospective study included 170 patients with Gleason grade 6 prostate cancer initially enrolled in an AS program between 2011 and 2019. Prostate mpMRI was performed using a 1.5 tesla (T) magnetic resonance imaging system with a 16-channel phased-array body coil. The protocol included T1-weighted, T2-weighted, diffusion-weighted, and dynamic contrast-enhanced imaging sequences. Uroradiology reports generated by a specialist were based on prostate imaging-reporting and data system (PI-RADS) version 2. Univariate and multivariate analyses were performed based on regression models. The reclassification rate at confirmatory biopsy was higher in patients with suspicious lesions on mpMRI (PI-RADS score ≥ 3) (n = 47) than in patients with non-suspicious mpMRIs (n = 61) and who did not undergo mpMRIs (n = 62) (66%, 26.2%, and 24.2%, respectively; p  Inclusion of mpMRI before the confirmatory biopsy is useful to stratify the risk of reclassification during the biopsy as well as to evaluate the risk of progression to active treatment during follow-up.
PB Korean Society of Radiology
YR 2020
FD 2020-09-21
LK http://hdl.handle.net/10668/16752
UL http://hdl.handle.net/10668/16752
LA en
NO Salguero J, Gómez-Gómez E, Valero-Rosa J, Carrasco-Valiente J, Mesa J, Martin C, et al. Role of Multiparametric Prostate Magnetic Resonance Imaging before Confirmatory Biopsy in Assessing the Risk of Prostate Cancer Progression during Active Surveillance. Korean J Radiol. 2021 Apr;22(4):559-567
DS RISalud
RD Apr 8, 2025