RT Journal Article T1 Updated Review on Ozone Therapy in Pain Medicine. A1 Hidalgo-Tallón, Francisco Javier A1 Torres-Morera, Luis Miguel A1 Baeza-Noci, Jose A1 Carrillo-Izquierdo, Maria Dolores A1 Pinto-Bonilla, Rosa K1 chronic pain K1 medical ozone K1 ozone injections K1 ozone therapy K1 pain medicine AB The use of medical ozone in the treatment of chronic pain is progressively expanding in Spain and today it is used both in public and private medical centers. However, there is a great lack of knowledge about this technology not only in primary care but also in medical specialties. Although its biochemical bases are well determined and there are various systematic reviews and meta-analyses in the literature that justify its use in pain medicine, some professionals still are prejudiced against it. The evidence level of using medical ozone according SIGN (Scotish Intercollegiate Guideline Network) criteria is similar or superior to most of the techniques used in a Pain Unit. In this paper, we have done a review on ozone therapy in pain medicine, compiling the evidence published about it. SN 1664-042X YR 2022 FD 2022-02-23 LK http://hdl.handle.net/10668/20715 UL http://hdl.handle.net/10668/20715 LA en DS RISalud RD Aug 6, 2025