RT Journal Article
T1 Severe thrombocytopenia induced by iodinated contrast after coronary angiography: The use of gadolinium contrast and intravascular ultrasound as an alternative to guide percutaneous coronary intervention
A1 Maria Cubero-Gomez, Jose
A1 Guerrero Marquez, Francisco J.
A1 Diaz-de la-Llera, Luis
A1 Fernandez-Quero, Monica
A1 Guisado-Rasco, Agustin
A1 Villa-Gil-Ortega, Manuel
K1 Imaging
K1 Intravascular ultrasound
K1 Contrast agents
K1 Percutaneous coronary intervention
K1 Nephrogenic systemic fibrosis
AB Acute contrast-induced thrombocytopenia is a rare event with the use of modern low osmolarity iodinated contrast media. The pathophysiological mechanism that causes platelet counts to drop has not been identified, but an immunological mechanism is suspected due to cytotoxicity after previous exposure to contrast. We report the case of a 47-year-old male patient with acute severe thrombocytopenia due to iodinated contrast media exposure. His platelet count after the procedure with the highest amount of contrast was zero, which is the lowest reported platelet count to date. Percutaneous coronary revascularization under both intravascular ultrasound and gadolinium contrast guidance was performed without complications. The most feared complication after the use of gadolinium is nephrogenic systemic fibrosis, especially in patients on hemodialysis. (C) 2016 Sociedade Portuguesa de Cardiologia. Published by Elsevier Espana, S.L.U. All rights reserved.
PB Elsevier doyma sl
SN 0870-2551
YR 2017
FD 2017-01-01
LK http://hdl.handle.net/10668/18873
UL http://hdl.handle.net/10668/18873
LA en
DS RISalud
RD Apr 17, 2025