RT Journal Article T1 A Novel Actinic Keratosis Field Assessment Scale for Grading Actinic Keratosis Disease Severity. A1 Dréno, Brigitte A1 Cerio, Rino A1 Dirschka, Thomas A1 Nart, Ignasi Figueras A1 Lear, John T A1 Peris, Ketty A1 de Casas, Andrés Ruiz A1 Kaleci, Shaniko A1 Pellacani, Giovanni AB Actinic keratosis (AK) lesions are surrounded by field cancerization (areas of subclinical, non-visible sun damage). Existing AK grading tools rely on AK counts, which are not reproducible. An Actinic Keratosis Field Assessment Scale (AK-FAS) for grading the severity of AK/field was developed. Standardized photographs of patients representing the full range of AK severity were collected. Six investigators independently rated each photograph according to 3 criteria: AK area (total skin area affected by AK lesions), hyperkeratosis and sun damage. Inter-rater reproducibility was good for all 3 criteria. Validation of the AK-FAS showed good reproducibility for AK area and hyperkeratosis, even for dermatologists untrained on use of the scale. In conclusion, the AK-FAS is objective, easy to use and implement, and reproducible. It incorporates assessment of the entire field affected by AK instead of relying on lesion counts. Use of the AK-FAS may standardize AK diagnosis, making it relevant to routine clinical practice. YR 2017 FD 2017 LK http://hdl.handle.net/10668/11226 UL http://hdl.handle.net/10668/11226 LA en DS RISalud RD Apr 8, 2025