TY - JOUR AU - Quintanal-Villalonga, Álvaro AU - Ferrer, Irene AU - Guruceaga, Elizabeth AU - Cirauqui, Cristina AU - Marrugal, Ángela AU - Ojeda, Laura AU - García, Santiago AU - Zugazagoitia, Jon AU - Muñoz-Galván, Sandra AU - Lopez-Rios, Fernando AU - Montuenga, Luis AU - Vicent, Silvestre AU - Molina-Pinelo, Sonia AU - Carnero, Amancio AU - Paz-Ares, Luis PY - 2020 DO - 10.1016/j.ebiom.2020.102683 UR - http://hdl.handle.net/10668/15186 T2 - EBioMedicine AB - Fibroblast growth factor receptor (FGFR)1 and FGFR4 have been associated with tumorigenesis in a variety of tumour types. As a therapeutic approach, their inhibition has been attempted in different types of malignancies, including lung cancer, and was... LA - en KW - FGFR inhibitors KW - FGFR1 KW - FGFR4 KW - N-cadherin KW - Predictive biomarker KW - Animals KW - Antineoplastic Agents KW - Benzamides KW - Biomarkers, Tumor KW - Cadherins KW - Carcinoma, Non-Small-Cell Lung KW - Cell Line, Tumor KW - Drug Resistance, Neoplasm KW - Female KW - Humans KW - Lung Neoplasms KW - Mice KW - Mice, Nude KW - Piperazines KW - Pyrazoles KW - Receptor, Fibroblast Growth Factor, Type 1 KW - Receptor, Fibroblast Growth Factor, Type 4 KW - Tumor Cells, Cultured TI - FGFR1 and FGFR4 oncogenicity depends on n-cadherin and their co-expression may predict FGFR-targeted therapy efficacy. TY - research article VL - 53 ER -