TY - JOUR AU - Stephens, Camilla AU - Lucena, M Isabel AU - Andrade, Raúl J PY - 2012 DO - 10.3389/fgene.2012.00253 UR - http://hdl.handle.net/10668/926 T2 - Frontiers in genetics AB - Despite stringent requirements for drug development imposed by regulatory agencies, drug-induced liver injury (DILI) is an increasing health problem and a significant cause for failure to approve drugs, market withdrawal of commercialized medications,... LA - en PB - Frontiers Research Foundation KW - Enfermedad Hepática Inducida por Drogas KW - Variación Genética KW - Genoma Humano KW - Estudio de Asociación del Genoma Completo KW - Preparaciones Farmacéuticas KW - Hígado KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Diseases::Digestive System Diseases::Liver Diseases::Drug-Induced Liver Injury KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome, Human KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Molecular Epidemiology::Genome-Wide Association Study KW - Medical Subject Headings::Chemicals and Drugs::Pharmaceutical Preparations KW - Medical Subject Headings::Anatomy::Digestive System::Liver TI - Genetic variations in drug-induced liver injury (DILI): resolving the puzzle. TY - research article ER -