RT Journal Article
T1 The associations of major foods and fibre with risks of ischaemic and haemorrhagic stroke: a prospective study of 418 329 participants in the EPIC cohort across nine European countries.
A1 Tong, Tammy Y N
A1 Appleby, Paul N
A1 Key, Timothy J
A1 Dahm, Christina C
A1 Overvad, Kim
A1 Olsen, Anja
A1 Tjønneland, Anne
A1 Katzke, Verena
A1 Kühn, Tilman
A1 Boeing, Heiner
A1 Karakatsani, Anna
A1 Peppa, Eleni
A1 Trichopoulou, Antonia
A1 Weiderpass, Elisabete
A1 Masala, Giovanna
A1 Grioni, Sara
A1 Panico, Salvatore
A1 Tumino, Rosario
A1 Boer, Jolanda M A
A1 Verschuren, W M Monique
A1 Quirós, J Ramon
A1 Agudo, Antonio
A1 Rodriguez-Barranco, Miguel
A1 Imaz, Liher
A1 Chirlaque, Maria-Dolores
A1 Moreno-Iribas, Conchi
A1 Engström, Gunnar
A1 Sonestedt, Emily
A1 Lind, Marcus
A1 Otten, Julia
A1 Khaw, Kay-Tee
A1 Aune, Dagfinn
A1 Riboli, Elio
A1 Wareham, Nicholas J
A1 Imamura, Fumiaki
A1 Forouhi, Nita G
A1 di Angelantonio, Emanuele
A1 Wood, Angela M
A1 Butterworth, Adam S
A1 Perez-Cornago, Aurora
K1 Diet
K1 Fibre
K1 Fruit
K1 Haemorrhagic stroke
K1 Ischaemic stroke
K1 Vegetables
AB To investigate the associations between major foods and dietary fibre with subtypes of stroke in a large prospective cohort. We analysed data on 418 329 men and women from nine European countries, with an average of 12.7 years of follow-up. Diet was assessed using validated country-specific questionnaires which asked about habitual intake over the past year, calibrated using 24-h recalls. Multivariable-adjusted Cox regressions were used to estimate hazard ratios (HRs) for ischaemic and haemorrhagic stroke associated with consumption of red and processed meat, poultry, fish, dairy foods, eggs, cereals, fruit and vegetables, legumes, nuts and seeds, and dietary fibre. For ischaemic stroke (4281 cases), lower risks were observed with higher consumption of fruit and vegetables combined (HR; 95% CI per 200 g/day higher intake, 0.87; 0.82-0.93, P-trend  Risk of ischaemic stroke was inversely associated with consumption of fruit and vegetables, dietary fibre, and dairy foods, while risk of haemorrhagic stroke was positively associated with egg consumption. The apparent differences in the associations highlight the importance of examining ischaemic and haemorrhagic stroke subtypes separately.
PB Oxford University Press
YR 2020
FD 2020-01-10
LK http://hdl.handle.net/10668/15151
UL http://hdl.handle.net/10668/15151
LA en
NO Tong TYN, Appleby PN, Key TJ, Dahm CC, Overvad K, Olsen A, et al. The associations of major foods and fibre with risks of ischaemic and haemorrhagic stroke: a prospective study of 418 329 participants in the EPIC cohort across nine European countries. Eur Heart J. 2020 Jul 21;41(28):2632-2640.
NO Analyses were supported by the UK Medical Research Council (MR/M012190/1), Cancer Research UK (C8221/A19170 and 570/A16491),and the Wellcome Trust (Our Planet Our Health, Livestock Environmentand People 205212/Z/16/Z). EPIC-CVD has been supported by theEuropean Union Framework 7 (HEALTH-F2-2012-279233), theEuropean Research Council (268834), the UK Medical Research Council(G0800270 and MR/L003120/1), the British Heart Foundation (SP/09/002and RG/08/014 and RG13/13/30194), and the UK National Institute ofHealth Research. The establishment of the study sub-cohort was supported by the EU Sixth Framework Programme (FP6) (grantLSHM_CT_2006_037197 to the InterAct project) and the Medical Research Council Epidemiology Unit (grants MC_UU_12015/1 andMC_UU_12015/5). The co-ordination of EPIC is financially supported bythe European Commission (DG-SANCO) and the International Agencyfor Research on Cancer. The national cohorts are supported by DanishCancer Society (Denmark); Ligue Contre le Cancer, Institut GustaveRoussy, Mutuelle Ge´ne´rale de l’Education Nationale, Institut National dela Sante´ et de la Recherche Me´dicale (INSERM) (France); GermanCancer Aid, German Cancer Research Center (DKFZ), Federal Ministryof Education and Research (BMBF), Deutsche Krebshilfe, DeutschesKrebsforschungszentrum and Federal Ministry of Education and Research(Germany); the Hellenic Health Foundation (Greece); AssociazioneItaliana per la Ricerca sul Cancro-AIRC-Italy and National ResearchCouncil (Italy); Dutch Ministry of Public Health, Welfare and Sports(VWS), LK Research Funds, Dutch Prevention Funds, Dutch ZON (ZorgOnderzoek Nederland), World Cancer Research Fund (WCRF);Regional Governments of Andalucı´a, Asturias, Basque Country, Murcia,Navarra, and the CERCA Program (Generalitat de Catalunya) (Spain);Swedish Cancer Society, Swedish Research Council and County Councilsof Ska˚ne and Va¨sterbotten (Sweden); Cancer Research UK (14136 toEPIC-Norfolk; C570/A16491 and C8221/A19170 to EPIC-Oxford), UKMedical Research Council (1000143 to EPIC-Norfolk, MR/M012190/1 toEPIC-Oxford, MC_UU_12015/1, and MC_UU_12015/520, and NIHRBiomedical Research Centre Cambridge: Nutrition, Diet, and LifestyleResearch Theme (IS-BRC-1215-20014) to the MRC Epidemiology UnitCambridge (NJW, NGF)
DS RISalud
RD Apr 12, 2025