TY  - JOUR
AU  - Baranes-Bachar, Keren
AU  - Levy-Barda, Adva
AU  - Oehler, Judith
AU  - Reid, Dylan A
AU  - Soria-Bretones, Isabel
AU  - Voss, Ty C
AU  - Chung, Dudley
AU  - Park, Yoon
AU  - Liu, Chao
AU  - Yoon, Jong-Bok
AU  - Li, Wei
AU  - Dellaire, Graham
AU  - Misteli, Tom
AU  - Huertas, Pablo
AU  - Rothenberg, Eli
AU  - Ramadan, Kristijan
AU  - Ziv, Yael
AU  - Shiloh, Yosef
PY  - 2018
DO  - 10.1016/j.molcel.2018.02.002
UR  - http://hdl.handle.net/10668/12204
T2  - Molecular cell
AB  - Double-strand breaks (DSBs) are critical DNA lesions that robustly activate the elaborate DNA damage response (DDR) network. We identified a critical player in DDR fine-tuning: the E3/E4 ubiquitin ligase UBE4A. UBE4A's recruitment to sites of DNA...
LA  - en
KW  - DNA damage
KW  - UBE4A
KW  - double-strand breaks
KW  - genome stability
KW  - ubiquitin
KW  - BRCA1 Protein
KW  - Carrier Proteins
KW  - DNA Breaks, Double-Stranded
KW  - DNA-Binding Proteins
KW  - HeLa Cells
KW  - Histone Chaperones
KW  - Humans
KW  - Nuclear Proteins
KW  - Recombinational DNA Repair
KW  - Ubiquitin-Protein Ligases
KW  - Ubiquitination
KW  - Ubiquitins
TI  - The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair.
TY  - research article
VL  - 69
ER  -