TY  - JOUR
AU  - Hernández, Gonzalo
AU  - Ramírez, María José
AU  - Minguillón, Jordi
AU  - Quiles, Paco
AU  - Ruiz de Garibay, Gorka
AU  - Aza-Carmona, Miriam
AU  - Bogliolo, Massimo
AU  - Pujol, Roser
AU  - Prados-Carvajal, Rosario
AU  - Fernández, Juana
AU  - García, Nadia
AU  - López, Adrià
AU  - Gutiérrez-Enríquez, Sara
AU  - Diez, Orland
AU  - Benítez, Javier
AU  - Salinas, Mónica
AU  - Teulé, Alex
AU  - Brunet, Joan
AU  - Radice, Paolo
AU  - Peterlongo, Paolo
AU  - Schindler, Detlev
AU  - Huertas, Pablo
AU  - Puente, Xose S
AU  - Lázaro, Conxi
AU  - Pujana, Miquel Àngel
AU  - Surrallés, Jordi
PY  - 2018
DO  - 10.1038/s41467-018-03433-3
UR  - http://hdl.handle.net/10668/12212
T2  - Nature communications
AB  - BRCA1 is a tumor suppressor that regulates DNA repair by homologous recombination. Germline mutations in BRCA1 are associated with increased risk of breast and ovarian cancer and BRCA1 deficient tumors are exquisitely sensitive to poly (ADP-ribose)...
LA  - en
KW  - BRCA1 Protein
KW  - Breast Neoplasms
KW  - Carrier Proteins
KW  - DNA Repair
KW  - DNA-Binding Proteins
KW  - Female
KW  - Homologous Recombination
KW  - Humans
KW  - Mutation
KW  - Nuclear Proteins
KW  - Poly (ADP-Ribose) Polymerase-1
KW  - Protein Binding
KW  - Proteins
KW  - RNA Caps
TI  - Decapping protein EDC4 regulates DNA repair and phenocopies BRCA1.
TY  - research article
VL  - 9
ER  -