TY  - JOUR
AU  - Puerto-Camacho, Pilar
AU  - Amaral, Ana Teresa
AU  - Lamhamedi-Cherradi, Salah-Eddine
AU  - Menegaz, Brian A
AU  - Castillo-Ecija, Helena
AU  - Ordóñez, José Luis
AU  - Domínguez, Saioa
AU  - Jordan-Perez, Carmen
AU  - Diaz-Martin, Juan
AU  - Romero-Pérez, Laura
AU  - Lopez-Alvarez, Maria
AU  - Civantos-Jubera, Gema
AU  - Robles-Frías, María José
AU  - Biscuola, Michele
AU  - Ferrer, Cristina
AU  - Mora, Jaume
AU  - Cuglievan, Branko
AU  - Schadler, Keri
AU  - Seifert, Oliver
AU  - Kontermann, Roland
AU  - Pfizenmaier, Klaus
AU  - Simón, Laureano
AU  - Fabre, Myriam
AU  - Carcaboso, Ángel M
AU  - Ludwig, Joseph A
AU  - de Álava, Enrique
PY  - 2018
DO  - 10.1158/1078-0432.CCR-18-0936
UR  - http://hdl.handle.net/10668/13173
T2  - Clinical cancer research : an official journal of the American Association for Cancer Research
AB  - Endoglin (ENG; CD105) is a coreceptor of the TGFβ family that is highly expressed in proliferating endothelial cells. Often coopted by cancer cells, ENG can lead to neo-angiogenesis and vasculogenic mimicry in aggressive malignancies. It exists both...
LA  - en
KW  - Animals
KW  - Antineoplastic Agents, Immunological
KW  - Bone Neoplasms
KW  - Cell Line
KW  - Disease Models, Animal
KW  - Dose-Response Relationship, Drug
KW  - Drug Evaluation, Preclinical
KW  - Endoglin
KW  - Gene Expression
KW  - Humans
KW  - Immunoconjugates
KW  - Matrix Metalloproteinase 14
KW  - Mice
KW  - Molecular Targeted Therapy
KW  - Precision Medicine
KW  - Sarcoma, Ewing
KW  - Xenograft Model Antitumor Assays
TI  - Preclinical Efficacy of Endoglin-Targeting Antibody-Drug Conjugates for the Treatment of Ewing Sarcoma.
TY  - research article
VL  - 25
ER  -