TY - JOUR AU - Zhou, Lisa AU - Leonard, Alexandra AU - Pavel, Ana B AU - Malik, Kunal AU - Raja, Aishwarya AU - Glickman, Jacob AU - Estrada, Yeriel D AU - Peng, Xiangyu AU - Del Duca, Ester AU - Sanz-Cabanillas, Juan AU - Ruano, Juan AU - Xu, Hui AU - Zhang, Ning AU - Wen, Huei-Chi AU - Gonzalez, Juana AU - Garcet, Sandra AU - Krueger, James G AU - Guttman-Yassky, Emma PY - 2019 DO - 10.1016/j.jaci.2019.01.015 UR - http://hdl.handle.net/10668/13466 T2 - The Journal of allergy and clinical immunology AB - Atopic dermatitis (AD) shows differential clinical presentation in older compared with younger patients. Nevertheless, changes in the AD molecular profile with age are unknown. We sought to characterize age-related changes in the AD profile. We... LA - en KW - Atopic dermatitis KW - T(H)1 KW - T(H)17 KW - T(H)2 KW - T(H)22 KW - aging KW - biomarker KW - filaggrin KW - hyperplasia KW - loricrin KW - skin KW - Adolescent KW - Adult KW - Aged KW - Aged, 80 and over KW - Aging KW - Cytokines KW - Dermatitis, Atopic KW - Female KW - Filaggrin Proteins KW - Gene Expression KW - Humans KW - Male KW - Middle Aged KW - Phenotype KW - Severity of Illness Index KW - Skin KW - Young Adult TI - Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis. TY - research article VL - 144 ER -