RT Journal Article
T1 Excess mortality in patients with schizophrenia spectrum disorders in Malaga (Spain): A cohort study
A1 Moreno-Küstner, Berta
A1 Guzman-Parra, Jose
A1 Pardo, Yolanda
A1 Sanchidrián, Yolanda
A1 Díaz-Ruiz, Sebastián
A1 Mayoral-Cleries, Fermin
K1 Health outcomes
K1 Psychosis
K1 Risk factors
K1 Schizophrenia
K1 Suicide
K1 Evaluación de resultado en la atención de salud
K1 Trastornos psicóticos
K1 Factores de riesgo
K1 Esquizofrenia
K1 Suicidio
AB AimsThere is evidence that patients with schizophrenia spectrum disorders present higher mortality in comparison with the general population. The aim of this study was to analyse the causes of mortality and sociodemographic factors associated with mortality, standardised mortality ratios (SMRs), life expectancy and potential years of life lost (YLL) in patients with schizophrenia spectrum disorders in Spain.MethodsThe study included a cohort of patients from the Malaga Schizophrenia Case Register (1418 patients; 907 males; average age 42.31 years) who were followed up for a minimum of 10 years (median = 13.43). The factors associated with mortality were analysed with a survival analysis using Cox's proportional hazards regression model.ResultsThe main causes of mortality in the cohort were circulatory disease (21.45%), cancer (17.09%) and suicide (13.09%). The SMR of the cohort was more than threefold that of the population of Malaga (3.19). The life expectancy at birth was 67.11 years old, which is more than 13 years shorter than that of the population of Malaga. The YLL was 20.74. The variables associated with a higher risk of mortality were age [adjusted hazard ratio (AHR) = 1.069, p < 0.001], male gender (AHR = 1.751, p < 0.001) and type of area of residence (p = 0.028; deprived urban zone v. non-deprived urban area, AHR = 1.460, p = 0.028). In addition, receiving welfare benefit status in comparison with employed status (AHR = 1.940, p = 0.008) was associated with increased mortality.ConclusionsThere is excess mortality in patients with schizophrenia spectrum disorders and also an association with age, gender, socioeconomic inequalities and receiving welfare benefits. Efforts directed towards improved living conditions could have a positive effect on reducing mortality.
PB Cambridge University Press
SN 2045-7960
YR 2021
FD 2021
LK http://hdl.handle.net/10668/4210
UL http://hdl.handle.net/10668/4210
LA en
NO Moreno-Küstner B, Guzman-Parra J, Pardo Y, Sanchidrián Y, Díaz-Ruiz S, Mayoral-Cleries F. Excess mortality in patients with schizophrenia spectrum disorders in Malaga (Spain): A cohort study. Epidemiol Psychiatr Sci. 2021;30:e11.
DS RISalud
RD Apr 7, 2025