TY - JOUR AU - Herishanu, Yair AU - Shaulov, Adir AU - Fineman, Riva AU - Bašić-Kinda, Sandra AU - Aviv, Ariel AU - Wasik-Szczepanek, Ewa AU - Jaksic, Ozren AU - Zdrenghea, Mihnea AU - Greenbaum, Uri AU - Mandac, Inga AU - Simkovic, Martin AU - Morawska, Marta AU - Benjamini, Ohad AU - Spacek, Martin AU - Nemets, Anatoly AU - Bairey, Osnat AU - Trentin, Livio AU - Ruchlemer, Rosa AU - Laurenti, Luca AU - Stanca Ciocan, Oana AU - Doubek, Michael AU - Shvidel, Lev AU - Dali, Nagib AU - Mirás, Fátima AU - De Meûter, Anne AU - Dimou, Maria AU - Mauro, Francesca R AU - Coscia, Marta AU - Bumbea, Horia AU - Szász, Róbert AU - Tadmor, Tamar AU - Gutwein, Odit AU - Gentile, Massimo AU - Scarfò, Lydia AU - Tedeschi, Alessandra AU - Sportoletti, Paolo AU - Gimeno Vázquez, Eva AU - Marquet, Juan AU - Assouline, Sarit AU - Papaioannou, Maria AU - Braester, Andrei AU - Levato, Luciano AU - Gregor, Michael AU - Rigolin, Gian M AU - Loscertales, Javier AU - Medina Perez, Angeles AU - Nijziel, Marten R AU - Popov, Viola M AU - Collado, Rosa AU - Slavutsky, Irma AU - Itchaki, Gilad AU - Ringelstein, Shimrit AU - Goldschmidt, Neta AU - Perry, Chava AU - Levi, Shai AU - Polliack, Aaron AU - Ghia, Paolo PY - 2020 DO - 10.1002/ajh.25766 UR - https://hdl.handle.net/10668/26637 T2 - American journal of hematology AB - In recent years, considerable progress has been made in frontline therapy for elderly/physically unfit patients with CLL. The combination of obinutuzumab and chlorambucil (O-Clb) has been shown to prolong progression free survival (PFS, median... LA - en KW - Aged KW - Aged, 80 and over KW - Antibodies, Monoclonal, Humanized KW - Antineoplastic Combined Chemotherapy Protocols KW - Chlorambucil KW - Chromosome Deletion KW - Chromosomes, Human, Pair 17 KW - Disease-Free Survival KW - Female KW - Humans KW - Leukemia, Lymphocytic, Chronic, B-Cell KW - Male KW - Retrospective Studies KW - Survival Rate KW - Tumor Suppressor Protein p53 TI - Frontline treatment with the combination obinutuzumab ± chlorambucil for chronic lymphocytic leukemia outside clinical trials: Results of a multinational, multicenter study by ERIC and the Israeli CLL study group. TY - research article VL - 95 ER -