RT Journal Article T1 Urinary Tartaric Acid, a Biomarker of Wine Intake, Correlates with Lower Total and LDL Cholesterol. A1 Domínguez-López, Inés A1 Parilli-Moser, Isabella A1 Arancibia-Riveros, Camila A1 Tresserra-Rimbau, Anna A1 Martínez-González, Miguel Angel A1 Ortega-Azorín, Carolina A1 Salas-Salvadó, Jordi A1 Castañer, Olga A1 Lapetra, José A1 Arós, Fernando A1 Fiol, Miquel A1 Serra-Majem, Lluis A1 Pintó, Xavier A1 Gómez-Gracia, Enrique A1 Ros, Emilio A1 Lamuela-Raventós, Rosa M A1 Estruch, Ramon K1 Mediterranean diet K1 PREDIMED K1 biomarkers K1 body fat K1 cardiovascular risk K1 lipid profile K1 menopause K1 polyphenols K1 tartaric acid AB Postmenopausal women are at higher risk of developing cardiovascular diseases due to changes in lipid profile and body fat, among others. The aim of this study was to evaluate the association of urinary tartaric acid, a biomarker of wine consumption, with anthropometric (weight, waist circumference, body mass index (BMI), and waist-to-height ratio), blood pressure, and biochemical variables (blood glucose and lipid profile) that may be affected during the menopausal transition. This sub-study of the PREDIMED (Prevención con Dieta Mediterránea) trial included a sample of 230 women aged 60-80 years with high cardiovascular risk at baseline. Urine samples were diluted and filtered, and tartaric acid was analyzed by liquid chromatography coupled to electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS). Correlations between tartaric acid and the study variables were adjusted for age, education level, smoking status, physical activity, BMI, cholesterol-lowering, antihypertensive, and insulin treatment, total energy intake, and consumption of fruits, vegetables, and raisins. A strong association was observed between wine consumption and urinary tartaric acid (0.01 μg/mg (95% confidence interval (CI): 0.01, 0.01), p-value YR 2021 FD 2021-08-22 LK http://hdl.handle.net/10668/18458 UL http://hdl.handle.net/10668/18458 LA en DS RISalud RD Jul 2, 2025