RT Journal Article
T1 Arterial Calcium Stimulation with Hepatic Venous Sampling in the Localization Diagnosis of Endogenous Hyperinsulinism
A1 Moreno-Moreno, Paloma
A1 Rosa Alhambra-Exposito, Maria
A1 Dulcinea Herrera-Martinez, Aura
A1 Palomares-Ortega, Rafel
A1 Zurera-Tendero, Luis
A1 Espejo Herrero, Juan Jose
A1 Angeles Galvez-Moreno, Maria
K1 Preoperative localization
K1 Management
K1 Insulinoma
K1 Injection
K1 Pancreas
K1 Tumors
AB Objective. The aim of this study was to assess the utility of arterial calcium stimulation with hepatic venous sampling (ASVS) in the localization diagnosis of endogenous hyperinsulinism. Patients and Methods. A retrospective descriptive study was performed including patients with endogenous hyperinsulinism who underwent ASVS. The histopathological diagnosis in patients who underwent a surgical procedure was used as the reference for the statistical study of the accuracy of this technique. Results. 30 patients were included with endogenous hyperinsulinism and nonconclusive imaging diagnosis was included. ASVS was performed in all cases. Surgery was performed in 20 cases. Insulinoma was removed in 19 patients; the location of all cases was detected in the ASVS. All cases of endogenous hyperinsulinism had a positive result for the ASVS, with this association being statistically significant (chi(2) = 15.771; p < 0.001). A good and statistically significant agreement was obtained between histopathologic diagnosis and ASVS results (𝐾 = 0.518, 𝑝 < 0.001). Conclusions. ASVS is a useful procedure in the localization diagnosis of endogenous hyperinsulinism undetected by other imaging tests. This technique allows the localization of intrapancreatic insulinomas and represents useful tool for the diagnosis and surgical management of these tumors.
PB Hindawi Limited
SN 1687-8337
YR 2016
FD 2016-08-04
LK http://hdl.handle.net/10668/19045
UL http://hdl.handle.net/10668/19045
LA en
NO Moreno-Moreno P, Alhambra-Expósito MR, Herrera-Martínez AD, Palomares-Ortega R, Zurera-Tendero L, Espejo Herrero JJ, et al. Arterial Calcium Stimulation with Hepatic Venous Sampling in the Localization Diagnosis of Endogenous Hyperinsulinism. Int J Endocrinol. 2016;2016:4581094
DS RISalud
RD Apr 7, 2025