TY  - JOUR
AU  - Martín-Serrano, Ángela
AU  - Gonzalez-Morena, Juan M.
AU  - Barbero, Nekane
AU  - Ariza, Adriana
AU  - Sánchez Gómez, Francisco J.
AU  - Pérez-Inestrosa, Ezequiel
AU  - Pérez-Sala, Dolores
AU  - Torres, Maria J.
AU  - Montañez, María I.
PY  - 2020
DO  - 10.3389/fphar.2020.594755
UR  - http://hdl.handle.net/10668/3580
T2  - Frontiers in Pharmacology
AB  - Clavulanic acid (CLV) and amoxicillin, frequently administered in combination, can be independently involved in allergic reactions. Protein haptenation with β-lactams is considered necessary to activate the immune system. The aim of this study was to...
LA  - en
PB  - Frontiers
KW  - Betalactam
KW  - Biotin tag
KW  - Biotinylation
KW  - Clavulanate
KW  - Drug allergy
KW  - Haptenation
KW  - Beta-lactamas
KW  - Biotina
KW  - Ácido clavulánico
KW  - Hipersensibilidad a las drogas
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amides::Lactams::beta-Lactams
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Biotinylation
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amides::Lactams::beta-Lactams::Clavulanic Acids::Clavulanic Acid
KW  - Medical Subject Headings::Diseases::Chemically-Induced Disorders::Drug-Related Side Effects and Adverse Reactions::Drug Hypersensitivity
KW  - Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Azoles::Imidazoles::Biotin
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Chemistry Techniques, Analytical::Mass Spectrometry
KW  - Medical Subject Headings::Anatomy::Hemic and Immune Systems::Immune System
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Blood Proteins::Immunoproteins
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Albumins::Ovalbumin::Avidin
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Globulins::Serum Globulins::Alpha-Globulins::Haptoglobins
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Physicochemical Phenomena::Solubility
TI  - Biotin-Labelled Clavulanic Acid to Identify Proteins Target for Haptenation in Serum: Implications in Allergy Studies
TY  - research article
ER  -