RT Journal Article
T1 ECLIM-SEHOP, a new platform to set up and develop international academic clinical trials for childhood cancer and blood disorders in Spain.
A1 Bautista, F
A1 Cañete, A
A1 Ramirez-Villar, G L
A1 Fernandez, J M
A1 Fuster, J L
A1 Diaz-de-Heredia, C
A1 Astigarraga, I
A1 Garcia-Ariza, M
A1 Rives, S
A1 Dapena, J L
A1 Marquez, C
A1 Molines, A
A1 Bermudez, M Del M
A1 Gallego, S
A1 Andres, M Del M
A1 Verdu-Amoros, J
A1 Hernandez, C
A1 Lopez, M
A1 Catala, A
A1 Lassaletta, A
A1 Cruz, O
A1 Ramirez, M
A1 Lendinez, F
A1 Carbone, A
A1 Gomez-Sirvent, J
A1 Tallon, M
A1 Acha, T
A1 Moreno, L
A1 Fernandez-Teijeiro, A
K1 Clinical research
K1 Clinical trials
K1 Drug development
K1 Pediatric hematology and oncology
AB Cancer and blood disorders in children are rare. The progressive improvement in survival over the last decades largely relies on the development of international academic clinical trials that gather the sufficient number of patients globally to elaborate solid conclusions and drive changes in clinical practice. The participation of Spain into large international academic trials has traditionally lagged behind of other European countries, mainly due to the burden of administrative tasks to open new studies, lack of financial support and limited research infrastructure in our hospitals. The objective of ECLIM-SEHOP platform (Ensayos Clínicos Internacionales Multicéntricos-SEHOP) is to overcome these difficulties and position Spain among the European countries leading the advances in cancer and blood disorders, facilitate the access of our patients to novel diagnostic and therapeutic approaches and, most importantly, continue to improve survival and reducing long-term sequelae. ECLIM-SEHOP provides to the Spanish clinical investigators with the necessary infrastructural support to open and implement academic clinical trials and registries. In less than 3 years from its inception, the platform has provided support to 20 clinical trials and 8 observational studies, including 8 trials and 4 observational studies where the platform performs all trial-related tasks (integral support: trial setup, monitoring, etc.) with more than 150 patients recruited since 2017 to these studies. In this manuscript, we provide baseline metrics for academic clinical trial performance that permit future comparisons. ECLIM-SEHOP facilitates Spanish children and adolescents diagnosed with cancer and blood disorders to access state-of-the-art diagnostic and therapeutic strategies.
PB Springer
YR 2019
FD 2019-10-09
LK http://hdl.handle.net/10668/14944
UL http://hdl.handle.net/10668/14944
LA en
NO Bautista F, Cañete A, Ramírez-Villar GL, Fernández JM, Fuster JL, Diaz de Heredia C, et al. ECLIM-SEHOP, a new platform to set up and develop international academic clinical trials for childhood cancer and blood disorders in Spain. Clin Transl Oncol. 2019 Dec;21(12):1763-1770
NO ECLIM-SEHOP is supported by the grant “Cáncer infantil y cánceres poco frecuentes 2018” from Asociación Española Contra el Cáncer (AECC) (Grant CICPF18016FERN 2018), Fundación Inocente Inocente, Federación Española de Padres de Niños con Cáncer, Asociación Pablo Ugarte and Fundación MAR. Other academic clinical trials conducted in Spain are supported by manynon-proft organizations to which we are also infnitely grateful as wellas the SCReN platform
DS RISalud
RD Apr 18, 2025