TY - JOUR AU - Urda, Daniel AU - Aragon, Francisco AU - Bautista, Rocio AU - Franco, Leonardo AU - Veredas, Francisco J AU - Claros, Manuel Gonzalo AU - Jerez, Jose Manuel PY - 2018 DO - 10.1186/s12918-018-0612-8 UR - http://hdl.handle.net/10668/13214 T2 - BMC systems biology AB - In RNA-Seq gene expression analysis, a genetic signature or biomarker is defined as a subset of genes that is probably involved in a given complex human trait and usually provide predictive capabilities for that trait. The discovery of new genetic... LA - en PB - Springer Nature KW - Biological knowledge KW - Biomarkers selection KW - Machine learning KW - Precision medicine KW - RNA-Seq KW - Biomarkers, tumor KW - Breast neoplasms KW - Female KW - Gene expression profiling KW - Humans KW - Linear models KW - Machine learning KW - Precision medicine KW - Sequence analysis, RNA TI - BLASSO: integration of biological knowledge into a regularized linear model. TY - research article VL - 12 ER -