RT Generic
T1 From cardiorenal syndromes to cardionephrology: a reflection by nephrologists on renocardiac syndromes
A1 Quiroga, Borja
A1 Ortiz, Alberto
A1 Navarro-Gonzalez, Juan F.
A1 Santamaria, Rafael
A1 de Sequera, Patricia
A1 Diez, Javier
K1 Acute kidney injury
K1 Cardionephrology
K1 Cardiorenal syndromes
K1 Chronic kidney disease
K1 Renocardiac syndromes
K1 Chronic kidney-disease
K1 Trimethylamine-n-oxide
K1 Mild renal-insufficiency
K1 Coronary flow reserve
K1 Growth-factor 23
K1 Heart-failure
K1 Cardiovascular events
K1 Inflammatory cytokines
K1 Pulmonary-hypertension
K1 Soluble tweak
AB Cardiorenal syndromes (CRS) are broadly defined as disorders of the heart and kidneys whereby acute or chronic dysfunction in one organ may induce acute or chronic dysfunction of the other. CRS are currently classified into five categories, mostly based on disease-initiating events and their acuity or chronicity. CRS types 3 and 4 (also called renocardiac syndromes) refer to acute and chronic kidney dysfunction resulting in acute and chronic heart dysfunction, respectively. The notion of renocardiac syndromes has broadened interest in kidney-heart interactions but uncertainty remains in the nephrological community's understanding of the clinical diversity, pathophysiological mechanisms and optimal management approaches of these syndromes. This triple challenge that renocardiac syndromes (and likely other cardiorenal syndromes) pose to the nephrologist can only be faced through a specific and demanding training plan to enhance his/her cardiological scientific knowledge and through an appropriate clinical environment to develop his/her cardiological clinical skills. The first must be the objective of the subspecialty of cardionephrology (or nephrocardiology) and the second must be the result of collaboration with cardiologists (and other specialists) in cardiorenal care units. This review will first consider various aspects of the challenges that renocardiac syndromes pose to nephrologists and, then, will discuss those aspects of cardionephrology and cardiorenal units that can facilitate an effective response to the challenges.
PB Oxford univ press
PB Oxford University Press
SN 2048-8505
YR 2022
FD 2022-04-30
LK http://hdl.handle.net/10668/19750
UL http://hdl.handle.net/10668/19750
LA en
NO Quiroga B, Ortiz A, Navarro-González JF, Santamaría R, de Sequera P, Díez J. From cardiorenal syndromes to cardionephrology: a reflection by nephrologists on renocardiac syndromes. Clin Kidney J. 2022 Apr 30;16(1):19-29
DS RISalud
RD Apr 7, 2025