TY - JOUR AU - Baglietto-Vargas, David AU - Prieto, Gilberto Aleph AU - Limon, Agenor AU - Forner, Stefania AU - Rodriguez-Ortiz, Carlos J AU - Ikemura, Kenji AU - Ager, Rahasson R AU - Medeiros, Rodrigo AU - Trujillo-Estrada, Laura AU - Martini, Alessandra C AU - Kitazawa, Masashi AU - Davila, Jose C AU - Cotman, Carl W AU - Gutierrez, Antonia AU - LaFerla, Frank M PY - 2018 DO - 10.1111/acel.12791 UR - http://hdl.handle.net/10668/12558 T2 - Aging cell AB - Alzheimer's disease (AD) is a devastating neurodegenerative disorder that impairs memory and causes cognitive and psychiatric deficits. New evidences indicate that AD is conceptualized as a disease of synaptic failure, although the molecular and... LA - en KW - AMPA receptor KW - Alzheimer's disease KW - Aβ KW - actin cytoskeleton KW - immunotherapy KW - synaptic impairment KW - Alzheimer Disease KW - Animals KW - Cytoskeleton KW - Disease Models, Animal KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Mice, Transgenic KW - Signal Transduction KW - Synaptic Transmission KW - alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid TI - Impaired AMPA signaling and cytoskeletal alterations induce early synaptic dysfunction in a mouse model of Alzheimer's disease. TY - research article VL - 17 ER -