RT Journal Article T1 Relationship between the Risk of Gastric Cancer and Adherence to the Mediterranean Diet According to Different Estimators. MCC-Spain Study A1 Alvarez-Alvarez, Laura A1 Vitelli-Storelli, Facundo A1 Rubin-Garcia, Maria A1 Aragones, Nuria A1 Ardanaz, Eva A1 Castano-Vinyals, Gemma A1 Obon-Santacana, Mireia A1 Dierssen-Sotos, Trinidad A1 Salas-Trejo, Dolores A1 Tardon, Adonina A1 Jimenez Moleon, Jose Juan A1 Alguacil, Juan A1 Dolores Chirlaque, Maria A1 Perez-Gomez, Beatriz A1 Pollan, Marina A1 Kogevinas, Manolis A1 Martin, Vicente K1 diet K1 Mediterranean K1 feeding behaviour K1 stomach neoplasms K1 Patterns K1 Epidemiology K1 Adenocarcinoma K1 Population K1 Indexes K1 Western K1 Food AB Dietary habits are one of the factors that influence the development of gastric cancer and, although it has been seen that the Mediterranean diet has a protective effect on this type of cancer, there are different indexes to assess the degree of adherence to this dietary pattern; this implies differences in the results obtained in the reduction of risk. The aim of this work was to assess the effect of adherence to the Mediterranean diet, measured with five different indexes, on the risk of gastric cancer.The aim was to assess the effect of adherence to the Mediterranean Diet, measured with five different indexes, on the risk of gastric cancer. Data come from the multicase-control study MCC-Spain, which included 354 gastric cancer cases and 3040 controls with data on diet. We used five indexes to evaluate adherence to the Mediterranean diet and assess the association between each pattern with the risk of gastric cancer, using multivariate logistic regression. The analyses were performed for the whole set of gastric cancer cases, by anatomical location (cardia and non-cardia) and by histological type (intestinal and diffuse). According to the used index, a high adherence protects one from gastric cancer (between 48% (aOR = 0.52; CI 95% = 0.28-0.94) and 75% (aOR = 0.25; CI 95% = 0.12-0.52)), from non-cardia (between 48% (aOR = 0.52; CI 95% = 0.36-0.75) and 65% (aOR = 0.35; CI 95% = 0.23-0.52)), and from the intestinal type (between 41% (aOR = 0.59; CI 95% = 0.36-0.95) and 72% (aOR = 0.28; CI 95% = 0.16-0.50)), but not from the diffuse type. In conclusion, high adherence to a Mediterranean diet pattern is a protective factor for the risk of gastric cancer, with greater adherence leading to greater protection. PB Mdpi YR 2021 FD 2021-11-01 LK https://hdl.handle.net/10668/25994 UL https://hdl.handle.net/10668/25994 LA en DS RISalud RD Apr 3, 2025