%0 Journal Article
%A Rodriguez, Carlos E
%A Palacios, Javier
%A Fajardo, Ignacio
%A Urdiales, Jose Luis
%A Le Guevel, Xavier
%A Lozano, Jose
%A Sanchez-Jimenez, Francisca
%T Conventional Matrices Loaded Onto a Graphene Layer Enhances MALDI-TOF/TOF Signal: Its Application to Improve Detection of Phosphorylated Peptides.
%D 2015
%U http://hdl.handle.net/10668/9645
%X This is the first study where graphene is used as a MALDI adjuvant in combination with the traditional matrix α-cyano-4-hydroxycinnamic acid (CHCA) to improve the signal intensity of peptide samples. Use of this amended matrix not only leads to increased signals but also to a higher number of peaks detected in complex samples. Additionally, the use of graphene has a stabilizing effect that can also be exploited to improve the detection of easily cleavable molecules. 
%K Graphene
%K MALDI-TOF/TOF
%K Phosphorylated peptides
%~