RT Journal Article
T1 Plasmapheresis as treatment for hyperlipidemic pancreatitis.
A1 Ramírez-Bueno, A
A1 Salazar-Ramírez, C
A1 Cota-Delgado, F
A1 Torre-Prados, M V de la
A1 Valdivielso, P
K1 Plasmapheresis
K1 Acute pancreatitis
K1 Hypertriglyceridemic pancreatitis
K1 Severe hypertriglyceridemia
K1 Plasmaféresis
K1 Pancreatitis
K1 Hiperlipidemias
K1 Enfermedad aguda
K1 Índice de severidad de la enfermedad
K1 Resultado del tratamiento
AB BACKGROUNDSevere hypertriglyceridemia with an accumulation of chylomicrons and triglyceride figures >1000 mg/dL can cause acute pancreatitis, a potentially fatal complication. The option of rapid reduction in triglyceride concentrations is attractive and possible with plasmapheresis.METHODSWe present the results of an analysis of 11 patients admitted to the intensive care unit with severe hypertriglyceridemic pancreatitis and treated with plasmapheresis. The procedure was repeated until serum triglycerides were below 1000 mg/dL. We recorded anthropometric, clinical data as well as final outcome.RESULTSIn eight patients a single plasma exchange was sufficient to reduce triglyceride figures <1000 mg/dL. Only three patients died, all with the worst severity indexes and who experienced the longest delay before the procedure.CONCLUSIONSOur results, together with a review of the literature, confirm the need for a randomized clinical trial to compare conventional treatment vs. plasmapheresis in patients with severe hypertriglyceridemic pancreatitis.
PB Elsevier
SN 0953-6205
YR 2014
FD 2014-02
LK http://hdl.handle.net/10668/1874
UL http://hdl.handle.net/10668/1874
LA en
NO Ramírez-Bueno A, Salazar-Ramírez C, Cota-Delgado F, Torre-Prados MV de la, Valdivielso P. Plasmapheresis as treatment for hyperlipidemic pancreatitis. Eur. J. Intern. Med.. 2014                         ; 25(2):160-3
NO Journal Article;
DS RISalud
RD Apr 11, 2025