RT Journal Article
T1 Deficits in executive and memory processes in delusional disorder: a case-control study
A1 Ibáñez-Casas, Inmaculada
A1 Portugal, Enrique de
A1 González, Nieves
A1 McKenney, Kathryn A
A1 Haro, Josep M
A1 Usall, Judith
A1 Pérez-García, Miguel
A1 Cervilla, Jorge A
K1 Neuropsychological Tests
K1 Schizophrenia, Paranoid
K1 Mental Recall
K1 Verbal Learning
K1 Pruebas neuropsicológicas
K1 Esquizofrenia paranoide
K1 Recuerdo mental
K1 Aprendizaje verbal
K1 Estudios de casos y controles
K1 Escolaridad
K1 Función Ejecutiva
AB OBJECTIVEDelusional disorder has been traditionally considered a psychotic syndrome that does not evolve to cognitive deterioration. However, to date, very little empirical research has been done to explore cognitive executive components and memory processes in Delusional Disorder patients. This study will investigate whether patients with delusional disorder are intact in both executive function components (such as flexibility, impulsivity and updating components) and memory processes (such as immediate, short term and long term recall, learning and recognition).METHODSA large sample of patients with delusional disorder (n = 86) and a group of healthy controls (n = 343) were compared with regard to their performance in a broad battery of neuropsychological tests including Trail Making Test, Wisconsin Card Sorting Test, Colour-Word Stroop Test, and Complutense Verbal Learning Test (TAVEC).RESULTSWhen compared to controls, cases of delusional disorder showed a significantly poorer performance in most cognitive tests. Thus, we demonstrate deficits in flexibility, impulsivity and updating components of executive functions as well as in memory processes. These findings held significant after taking into account sex, age, educational level and premorbid IQ.CONCLUSIONSOur results do not support the traditional notion of patients with delusional disorder being cognitively intact.
PB Public Library of Science
YR 2013
FD 2013-08
LK http://hdl.handle.net/10668/1948
UL http://hdl.handle.net/10668/1948
LA en
NO Ibáñez-Casas I, Portugal E de, González N, McKenney KA, Haro JM, Usall J, et al. Deficits in executive and memory processes in delusional disorder: a case-control study. PLoS ONE. 2013; 8(7):e67341
NO Journal Article; Research Support, Non-U.S. Gov't;
DS RISalud
RD Apr 10, 2025