TY  - JOUR
AU  - Alvarez-Larrán, Alberto
AU  - Kerguelen, Ana
AU  - Hernández-Boluda, Juan C
AU  - Pérez-Encinas, Manuel
AU  - Ferrer-Marín, Francisca
AU  - Bárez, Abelardo
AU  - Martínez-López, Joaquín
AU  - Cuevas, Beatriz
AU  - Mata, M Isabel
AU  - García-Gutiérrez, Valentín
AU  - Aragües, Pilar
AU  - Montesdeoca, Sara
AU  - Burgaleta, Carmen
AU  - Caballero, Gonzalo
AU  - Hernández-Rivas, J Angel
AU  - Durán, M Antonia
AU  - Gómez-Casares, M Teresa
AU  - Besses, Carles
AU  - Grupo Español de Enfermedades Mieloproliferativas Filadelfia Negativas (GEMFIN)
PY  - 2015
DO  - 10.1111/bjh.13886
UR  - https://hdl.handle.net/10668/26696
T2  - British journal of haematology
AB  - The clinical significance of resistance/intolerance to hydroxycarbamide (HC) was assessed in a series of 890 patients with polycythaemia vera (PV). Resistance/intolerance to HC was recorded in 137 patients (15·4%), consisting of: need for phlebotomies...
LA  - en
KW  - hydroxycarbamide
KW  - myeloproliferative neoplasms
KW  - polycythaemia vera
KW  - resistance/intolerance
KW  - response criteria
KW  - Adolescent
KW  - Adult
KW  - Aged
KW  - Aged, 80 and over
KW  - Drug Resistance
KW  - Drug Tolerance
KW  - Female
KW  - Humans
KW  - Hydroxyurea
KW  - Kaplan-Meier Estimate
KW  - Leukocyte Count
KW  - Leukopenia
KW  - Male
KW  - Middle Aged
KW  - Nucleic Acid Synthesis Inhibitors
KW  - Polycythemia Vera
KW  - Prognosis
KW  - Registries
KW  - Retrospective Studies
KW  - Treatment Outcome
KW  - Young Adult
TI  - Frequency and prognostic value of resistance/intolerance to hydroxycarbamide in 890 patients with polycythaemia vera.
TY  - research article
VL  - 172
ER  -